Double-balloon enteroscopy in patients with GI bleeding of obscure origin

Manabe, Noriaki; Tanaka, Shinji; Fukumoto, Atsushi; Nakao, Masakazu; Kamino, Daisuke; Chayama, Kazuaki

doi:10.1016/j.gie.2005.12.020

Cited by 96 publications

(51 citation statements)

References 17 publications

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“…It is considered the gold standard for therapeutic intervention of many small bowel disorders in OGIB [49] . The diagnostic yield and treatment success of DBE for OGIB in published literature ranges from 60%-81% and 43%-84% respectively [10,[50][51][52][53][54][55][56][57][58][59][60] . The variation in diagnostic yield is a result of differences in DBE timing, inclusion criteria and definitions of a significant finding [61] .…”

Section: Capsule Endoscopymentioning

confidence: 99%

Evaluation and outcomes of patients with obscure gastrointestinal bleeding

Santhakumar

Liu

2014

WJGP

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Core tip: This article examines the role of current diagnostic modalities for the investigation of obscure gastrointestinal bleeding (OGIB) and outcomes in patients undergoing these investigations. Capsule endoscopy and double balloon enteroscopy remain the cornerstone of diagnostic and therapeutic management. The diagnostic and therapeutic capabilities of certain modalities are influenced by the nature of bleeding in OGIB. Longterm outcome data in patients with OGIB is limited but is most promising for capsule endoscopy.Santhakumar C, Liu K. Evaluation and outcomes of patients with obscure gastrointestinal bleeding. World J Gastrointest Pathophysiol 2014; 5(4

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Section: Capsule Endoscopymentioning

confidence: 99%

Evaluation and outcomes of patients with obscure gastrointestinal bleeding

Santhakumar

Liu

2014

WJGP

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“…On the other hand, the double-balloon endoscopy (DBE) method of Yamamoto et al [4] allows to-and-fro observation and even therapeutic intervention can be performed. The usefulness of DBE for the diagnosis and treatment of small bowel lesions has been documented [5,6,7]. However, the long-term outcome after DBE in patients with OGIB is not completely known.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Outcome after Double-Balloon Endoscopy in Patients with Obscure Gastrointestinal Bleeding

Fujita¹,

Manabe²,

Honda³

et al. 2010

Digestion

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Background and Aims: There are limited data concerning the clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) after double-balloon endoscopy (DBE). The aim of the present study was to evaluate the long-term outcome of patients with OGIB after DBE. Patients and Methods: Eighty-seven consecutive patients with OGIB (47 men and 40 women; mean age 65.3 years) underwent DBE between July 2006 and December 2009. The criteria for assessment included documented iron deficiency anemia/occult or obscure small intestinal bleeding, and overt small intestinal bleeding. They were followed for a mean period of 41.4 months after DBE, and were divided into two groups according to their outcome, that is a good clinical course group (GC group) and a poor clinical course group (PC group). The clinical characteristics associated with rebleeding after DBE were analyzed by comparison of these two groups. Results: The source of bleeding was identified in 40 patients (46.0%) and endoscopic treatment was required in 21 of them (52.5%). The most frequent source of bleeding was ulcers/erosions (18.4%). During the follow-up period, 39 patients (44.8%) experienced bleeding and/or persistent iron deficiency anemia after DBE, while 48 patients did not. There were no significant differences of clinical characteristics between the two groups. However, there were more patients with diverticular bleeding in the GC group than the PC group, and there were significantly more patients with treatable small intestinal tumors/polyps in the GC group. There were also more patients with normal DBE findings in the GC group. Conclusion: This study demonstrated that the rebleeding rate after DBE varies depending on the source of bleeding.

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“…Indeed, these approaches have mainly been used to detect obscure bleeding in the small intestine. [6][7][8] Such lesions have also been treated by DBE. [9][10][11] Also, DBE has been performed to detect some endoscopic features of the small intestine under different pathological conditions.…”

Section: Introductionmentioning

confidence: 99%