“…For LM true bifurcation lesions, the current PCI therapy in clinical settings is still primarily singlestenting or double-stenting intervention, but these two methods do not reduce the incidence of in-stent restenosis, possibly due to factors such as vascular anatomy (the proximal lesion involves longer vessel length and a wider angle of division), hemodynamics (large local blood flow), stent deformation, and reduced drug coverage [19][20][21][22]. Among these, stent thrombosis after single stenting may be caused by the protrusion of stent struts in the bifurcation lesion [23], and single stenting applies only for stent placement in the LM or LAD, while the LCX will be subject to plaque compression after stenting to various degrees, resulting in aggravated stenosis, which might eventually lead to total LCX occlusion.…”