Double-Blind Randomized Controlled Trial

Resteghini, Peter; Khanbhai, Tamim; Mughal, Shabaaz; Sivardeen, Z

doi:10.1097/jsm.0000000000000184

Cited by 20 publications

(6 citation statements)

References 25 publications

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“…All the articles included in the present review involved 326 individuals, most of whom were athletes practicing various sports and aged between 18 and 55 years. Functionality with VISA-p was assessed in eight studies [ 8 , 21 , 23 , 34 – 38 ], and pain was evaluated using a numeric scale in all studies except one [ 38 ]. The main features of these studies are summarized in Table 1 .…”

Section: Resultsmentioning

confidence: 99%

“…This study revealed that there are no differences between the groups neither in the short nor in the long term. Along these lines, Resteghini et al [ 38 ] compared the effectiveness of AB versus saline and found no differences between groups. Finally, this review is in line with a previous study [ 21 ] that reported that PRP was not superior to placebo or DN at a 6-month follow-up for tendinopathy treatment.…”

Section: Discussionmentioning

confidence: 99%

“…The studies previously mentioned in this review testing cell therapy, PRP, DN, and AB [ 21 , 31 , 34 , 35 , 37 , 38 ] were accompanied by a standardized program of exercise during treatment, most of them with EE which is until now, the gold standard technique for the treatment of this injury. However, several studies have shown that HSR is more effective than EE [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

“…In this study, no significant differences were found between the three groups in the short term, failing to demonstrate any significant benefit of LP-PRP or LR-PRP over saline injection. Eventually, the effectiveness of the autologous blood (AB) injections was studied in a recent RCT [ 38 ], showing that both AB and saline groups experienced a significant improvement in symptoms, with nonsignificant statistical differences between groups.…”

Section: Reviewmentioning

confidence: 99%

“…Regarding pharmacological treatments, several studies [ 8 , 23 , 38 – 40 ] applied different drug infiltrations protocols, including steroids and sclerosing agents. A study comparing steroids with placebo showed an improvement at 6 months in the steroids group for pain measured with a numeric rating scale and a decrease of tendon thickness, maintaining this effect at 6 months [ 39 ].…”

Section: Reviewmentioning

confidence: 99%

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The Effectiveness of Minimally Invasive Techniques in the Treatment of Patellar Tendinopathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

López-Royo

Ortiz-Lucas

Gómez-Trullén

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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The aim was to determine the effectiveness of minimally invasive techniques (MIT) in patients with patellar tendinopathy. Database searches were performed for randomized controlled trials (RCTs) in electronic databases (WOS, Cochrane Central, SportDiscus, and Medline via PubMed and PEDro). The inclusion criteria used were published in English or Spanish and involving adults with patellar tendinopathy (pain on the inferior pole of the patella for a minimum of 3 months), with at least one group receiving MIT. The quality of the relevant RCTs was evaluated using the PEDro scale. The primary outcome was functionality using the VISA-p questionnaire. Secondary outcome was focused on pain. A total of 1164 studies were screened for possible inclusion in our systematic review. Finally, 10 RCTs were included with a total of 326 individuals. Five RCTs were included in the meta-analysis. The quality assessment revealed that all the studies included were considered to possess high methodological quality. All studies analyzing MIT such as platelet-rich plasma (PRP), dry needling, or skin-derived tenocyte-like cells, when combined with exercise, proved to be effective for patellar tendinopathy. Moreover, the PRP technique with doses greater than 4 mL together and combined with an exercise program lasting over 6 weeks obtained better results in functionality and pain than other treatments in the short term. However, in the long term, dry needling and skin-derived tenocyte-like cells are more effective than PRP. Although the infiltration of drugs was effective at posttreatment, these improvements were not maintained over time and may have secondary effects. Although there are no RCTs analyzing the effectiveness of MIT like percutaneous needle electrolysis, there has been an increasing number of publications achieving excellent results in the last years. However, it is necessary to develop RCTs analyzing not only the effect but also comparing the effectiveness between different MIT such as dry needling and percutaneous needle electrolysis.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

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The Effectiveness of Minimally Invasive Techniques in the Treatment of Patellar Tendinopathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

López-Royo

Ortiz-Lucas

Gómez-Trullén

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Dutch multidisciplinary guideline on anterior knee pain: Patellofemoral pain and patellar tendinopathy

Ophey,

Koëter,

van Ooijen

et al. 2024

Knee surg. sports traumatol. arthrosc.

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PurposeThe purpose of this study was to develop a multidisciplinary guideline for patellofemoral pain (PFP) and patellar tendinopathy (PT) to facilitate clinical decision‐making in primary and secondary care.MethodsA multidisciplinary expert panel identified questions in clinical decision‐making. Based on a systematic literature search, the strength of the scientific evidence was determined according to the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) method and the weight assigned to the considerations by the expert panel together determined the strength of the recommendations.ResultsAfter confirming PFP or PT as a clinical diagnosis, patients should start with exercise therapy. Additional conservative treatments are indicated only when exercise therapy does not result in clinically relevant changes after six (PFP) or 12 (PT) weeks. Pain medications should be reserved for cases of severe pain. The additional value of imaging assessments for PT is limited. Open surgery is reserved for very specific cases of nonresponders to exercise therapy and those requiring additional conservative treatments. Although the certainty of evidence regarding exercise therapy for PFP and PT had to be downgraded (‘very low GRADE’ and ‘low GRADE’), the expert panel advocates its use as the primary treatment strategy. The panel further formulated weaker recommendations regarding additional conservative treatments, pain medications, imaging assessments and open surgery (‘very low GRADE’ to ‘low GRADE’ assessment or absence of scientific evidence).ConclusionThis guideline recommends starting with exercise therapy for PFP and PT. The recommendations facilitate clinical decision‐making, and thereby optimizing treatment and preventing unnecessary burdens, risks and costs to patients and society.Level of EvidenceLevel V, clinical practice guideline.

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Evaluation and Treatment of Soft Tissue Overuse Injuries

Walrod

2016

Endurance Sports Medicine

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Double-Blind Randomized Controlled Trial

Abstract: This research showed that tendon fenestration is an alternative cost-effective treatment for recalcitrant PT.

Cited by 20 publications

References 25 publications

The Effectiveness of Minimally Invasive Techniques in the Treatment of Patellar Tendinopathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

The Effectiveness of Minimally Invasive Techniques in the Treatment of Patellar Tendinopathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Dutch multidisciplinary guideline on anterior knee pain: Patellofemoral pain and patellar tendinopathy

Evaluation and Treatment of Soft Tissue Overuse Injuries

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