2021
DOI: 10.2106/jbjs.rvw.21.00082
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Double Crush Syndrome of the Upper Extremity

Abstract: The double crush hypothesis originally proposed that compression of a peripheral nerve at a proximal site increases its susceptibility to additional distal lesions.The etiology of double crush syndrome is likely multifactorial as mechanical, systemic, pharmacologic, or environmental factors may increase a patient’s susceptibility to this syndrome.To date, there remains no standardized definition of double crush syndrome, and there is no consensus on its exact pathophysiology or diagnostic criteria.Patients wit… Show more

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Cited by 11 publications
(4 citation statements)
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“…Although the proper order of surgeries in cases of double crush syndrome with L5 radiculopathy and CPNE remains inconclusive, the more severe side should be treated first according to the same pathology in the upper extremities. 28 , 29 ) If the severity of both pathologies is similar, CPNE may be treated first because it can be done less invasively with local anesthesia. We need to give enough information about both pathologies to patients preoperatively.…”
Section: Discussionmentioning
confidence: 99%
“…Although the proper order of surgeries in cases of double crush syndrome with L5 radiculopathy and CPNE remains inconclusive, the more severe side should be treated first according to the same pathology in the upper extremities. 28 , 29 ) If the severity of both pathologies is similar, CPNE may be treated first because it can be done less invasively with local anesthesia. We need to give enough information about both pathologies to patients preoperatively.…”
Section: Discussionmentioning
confidence: 99%
“…Ambas teorías sugieren que el atrapamiento de un nervio afecta el transporte axoplasmático, provocando que otras áreas del nervio sean más susceptibles a atrapamiento 4,[6][7][8] .…”
Section: Neuropatías Por Atrapamientounclassified
“…Both theories suggest that nerve entrapment affects axoplasmic transport, making other areas of the nerve more susceptible to entrapment 4,[6][7][8] .…”
Section: Entrapment Neuropathiesmentioning
confidence: 99%