Double-differential fragmentation cross-section measurements of 95 MeV/nucleon<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msup><mml:mrow /><mml:mn>12</mml:mn></mml:msup></mml:math>C beams on thin targets for hadron therapy

Dudouet, J.; Juliani, D.; Labalme, M.; Cussol, D.; Angélique, J. C.; Braunn, B.; Colin, J.; Finck, C.; Fontbonne, J.M.; Guérin, H.; Henriquet, P.; Krimmer, J.; Rousseau, M.; Saint‐Laurent, M. G.; Salvador, S.

doi:10.1103/physrevc.88.024606

Cited by 63 publications

(76 citation statements)

References 22 publications

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“…Such measurements have been performed under different experimental conditions, covering in some cases only the very forward fragment emission region and in other cases a few other fixed-angle configurations. Recently a double-differential cross-section measurement in thin targets was performed using 12 C ions of 95 MeV/nucleon kinetic energy as projectiles, with an experimental setup able to cover a large angular range: 0 • [13] and 4 • -45 • [14].…”

Section: Introductionmentioning

confidence: 99%

Measurement of fragmentation cross sections ofC12ions on a thin gold target with the FIRST apparatus

Toppi¹,

Abou-Haïdar²,

Agodi³

et al. 2016

Phys. Rev. C

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A detailed knowledge of the light ions interaction processes with matter is of great interest in basic and applied physics. As an example, particle therapy and space radioprotection require highly accurate fragmentation cross-section measurements to develop shielding materials and estimate acute and late health risks for manned missions in space and for treatment planning in particle therapy. The Fragmentation of Ions Relevant for Space and Therapy experiment at the Helmholtz Center for Heavy Ion research (GSI) was designed and built by an international collaboration from France, Germany, Italy, and Spain for studying the collisions of a 12 C ion beam with thin targets. The collaboration's main purpose is to provide the double-differential cross-section measurement of carbon-ion fragmentation at energies that are relevant for both tumor therapy and space radiation protection applications. Fragmentation cross sections of light ions impinging on a wide range of thin targets are also essential to validate the nuclear models implemented in MC simulations that, in such an energy range, fail to reproduce the data with the required accuracy. This paper presents the single differential carbon-ion fragmentation cross sections on a thin gold target, measured as a function of the fragment angle and kinetic energy in the forward * Corresponding author: alessio.sarti@uniroma1.it 2469-9985/2016/93(6)/064601 (21) 064601-1 ©2016 American Physical Society M. TOPPI et al. PHYSICAL REVIEW C 93, 064601 (2016) angular region (θ 6 • ), aiming to provide useful data for the benchmarking of the simulation softwares used in light ions fragmentation applications. The 12 C ions used in the measurement were accelerated at the energy of 400 MeV/nucleon by the SIS (heavy ion synchrotron) GSI facility.

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Section: Introductionmentioning

confidence: 99%

Measurement of fragmentation cross sections ofC12ions on a thin gold target with the FIRST apparatus

Toppi¹,

Abou-Haïdar²,

Agodi³

et al. 2016

Phys. Rev. C

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“…Fig. 1 shows comparison of isotopic differential fragment production cross sections at 95 MeV/nucleon calculated using JQMD, JQMD-2.0 and those measured by Dudouet et al [12,13].…”

Section: Resultsmentioning

confidence: 99%

Analysis of angular distribution of fragments in relativistic heavy-ion collisions by quantum molecular dynamics

Ogawa

Sato

Hashimoto

et al. 2016

EPJ Web of Conferences

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To predict angular distribution of fragments produced in nucleusnucleus collisions, JAERI quantum molecular dynamics model (JQMD) was improved. Because JQMD underestimated fragments in the forward angle, which were mainly produced by peripheral collisions, JQMD was revised so as to simulate peripheral collisions accurately. Density-dependent in-medium effect and relativistic effect on nucleonnucleon interactions were incorporated for this purpose. The revised version of JQMD coupled with a statistical decay model was used to calculate differential fragment production cross sections measured in earlier studies. Comparison of the measured data and calculation by the revised and old JQMD showed that the revised JQMD can predict fragment angular distribution better than old JQMD. Particularly, agreement of fragment yield in the forward angle is substantially improved.

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“…The authors of ref. [6] have already shown that the cross section on H can be extracted by subtraction from the coupled data obtained using both CH 2 and pure C target.…”

Section: The Foot Experimentsmentioning

confidence: 99%

“…onto hydrogen enriched target, such as CH 2 , as already adopted in ref. [8,6]. Secondary fragments will have boosted energy and longer range, making the detection easier.…”

Section: The Foot Experimentsmentioning

confidence: 99%

“…In recent years some experiments have been dedicated to the study of projectile fragmentation for 12 C ions, however this program was carried out only for a few energies [6,7]. On the other hand the process of target fragmentation, which is the only relevant process of this kind in proton therapy, so far has been almost completely neglected.…”

Section: Introductionmentioning

confidence: 99%

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The FOOT (Fragmentation Of Target) Experiment

Battistoni¹,

Alexandrov²,

Argirò³

et al. 2017

Proceedings of 55th International Winter Meeting on Nuclear Physics — PoS(BORMIO2017)

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Particle therapy uses protons or 12 C beams for the treatment of deep-seated solid tumors. Due to the features of the energy deposition of charged particles in matter, a limited amount of dose is released to the healthy tissue in the beam entrance region, while the maximum of the dose is released to the tumor at the end of the beam range, in the Bragg peak region. However nuclear interactions between beam and patient tissues induce fragmentation both of projectile and target. This has to be carefully taken into account since different ions have different effectiveness in producing a biological damage. In 12 C treatments the main concern are long range forward emitted secondary ions produced in projectile fragmentation that release dose in the healthy tissue after the tumor. Instead, in a proton treatment, the target fragmentation produces low energy, short range fragments along all the beam range. The FOOT experiment (FragmentatiOn Of Target) is designed to study these processes. Target nuclei ( 16 O, 12 C) fragmentation induced by 150-250 MeV proton beam will be studied by means of the inverse kinematic approach. 16 O, 12 C therapeutic beams, at the quoted kinetic energy per nucleon, collide on graphite and hydrocarbons target. The cross section on Hydrogen can be then extracted by subtraction. This configuration explores also the projectile fragmentation of these 16 O, 12 C beams, or other ions of therapeutic interest, such as 4 He for instance.The detector includes a magnetic spectrometer based on silicon pixel and strip detectors, a scintillating crystal calorimeter able to stop the heavier produced fragments, and a ∆E detector, with TOF capability, to achieve the needed energy resolution and particle identification. In addition to the electronic apparatus, an alternative setup based on the concept of the "Emulsion Cloud Chamber", coupled with the interaction region of the electronic FOOT setup, will provide the measurement of lighter charged fragments: protons, deuterons, tritons and Helium nuclei.

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Double-differential fragmentation cross-section measurements of 95 MeV/nucleon12C beams on thin targets for hadron therapy

Cited by 63 publications

References 22 publications

Measurement of fragmentation cross sections ofC12ions on a thin gold target with the FIRST apparatus

Measurement of fragmentation cross sections ofC12ions on a thin gold target with the FIRST apparatus

Analysis of angular distribution of fragments in relativistic heavy-ion collisions by quantum molecular dynamics

The FOOT (Fragmentation Of Target) Experiment

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