Double-Low Dose Protocol of Computed Tomography Pulmonary Angiography (CTPA) in the Diagnosis of Pulmonary Embolism: A Feasible Approach for Reduction of Both Contrast Medium and Radiation Doses

Aldosari, Sultan; Moudi, Mansour Al; Sun, Zhonghua

doi:10.17140/hroj-4-139

Cited by 4 publications

(2 citation statements)

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“…20 As an added benefit, low kV technique can improve coronary arteries' enhancement via increasing photoelectric events in low energy photons and their higher attenuation by contrast media. 17,[21][22][23][24] Therefore, low kV scanning allows reduction in contrast medium concentration, because of iodine k-edge absorption. 20,[25][26][27][28][29] This parallels with minimized risk of CIN, mainly in diabetic patients who consume metformin.…”

Section: Introductionmentioning

confidence: 99%

“…It has been suggested that lowering kV based on body mass index would be a practical approach to decrease patient dose without sacrificing the image quality . As an added benefit, low kV technique can improve coronary arteries’ enhancement via increasing photoelectric events in low energy photons and their higher attenuation by contrast media . Therefore, low kV scanning allows reduction in contrast medium concentration, because of iodine k‐edge absorption .…”

Section: Introductionmentioning

confidence: 99%

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Coronary CT angiography by modifying tube voltage and contrast medium concentration: Evaluation of image quality and radiation dose

et al. 2019

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Background Currently, there is an increasing interest in noninvasive imaging of cardiovascular system such as computed tomography coronary angiography (CCTA). The risks of radiation‐induced cancer and contrast‐induced nephropathy (CIN) have always been regarded as concerns which increased demand for CCTA using reduced radiation dose and iodine intake. We aimed to evaluate the image quality and radiation dose of CCTA by modifying tube voltage and concentration of contrast media. Methods The present study includes 105 patients who underwent CCTA for clinical indications. Specific inclusion and exclusion criteria in terms of patient's weight, body mass index, calcium score, and stenting were used. First group of patients scanned by 120 kV and 370 mg I/mL contrast medium, compared with second and third groups for which scanning was performed using 100 kV and 370 mg I/mL and 100 kV and 300 mg I/mL, respectively. Image quality was evaluated both subjectively and objectively. The effective dose and iodine intake were also measured. Results Using low kV protocols led to radiation dose reduction up to 38% and applying low contrast medium concentration with consequent reduced iodine intake up to 21%. Moreover, there were significant differences in image quality of new scanning protocols. Conclusion Reduction in tube voltage with lowering of contrast medium concentration can reduce radiation dose and iodine intake with acceptable image quality.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Coronary CT angiography by modifying tube voltage and contrast medium concentration: Evaluation of image quality and radiation dose

et al. 2019

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Chest X-ray in Right Heart Disease

Sun

Liu

Fan

2018

Right Heart Pathology

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Double low-dose computed tomography pulmonary angiography in the diagnosis of pulmonary embolism

Aldosari

Al-Mantshari

AlQahtani

et al. 2019

J. Phys.: Conf. Ser.

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The purpose of this study is to investigate the feasibility of double low-dose (low radiation and low contrast medium doses) computed tomography pulmonary angiography (CTPA) in the diagnosis of pulmonary embolism. This retrospective study involved analysis of 59 patients undergoing 64- and 128-slice CTPA examinations which were scanned with a pitch of 0.9 and 100 and 120 kVp, respectively, while flash mode of CTPA was done with a pitch of 3.2 and 120 kVp. There were no significant differences in image quality assessment between the low kVp and standard kVp or high-pitch CTPA protocols (p=0.181-0.186). The mean effective dose for the 100 kVp protocol was significantly lower than that for the120 kVp and the flash mode protocols (p < 0.001). The contrast medium was between 35-45 ml for the 100 and 120 kVp protocols, and 20-30 ml for the 120 kVp flash mode protocol. Double low-dose CT pulmonary angiography is feasible for detection of pulmonary embolism with acquisition of diagnostic images.

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Double-Low Dose Protocol of Computed Tomography Pulmonary Angiography (CTPA) in the Diagnosis of Pulmonary Embolism: A Feasible Approach for Reduction of Both Contrast Medium and Radiation Doses

Cited by 4 publications

References 35 publications

Coronary CT angiography by modifying tube voltage and contrast medium concentration: Evaluation of image quality and radiation dose

Coronary CT angiography by modifying tube voltage and contrast medium concentration: Evaluation of image quality and radiation dose

Chest X-ray in Right Heart Disease

Double low-dose computed tomography pulmonary angiography in the diagnosis of pulmonary embolism

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