Double Orifice Mitral Valve and Bicuspid Aortic Valve: Pieces of the Same Single Puzzle?

Şaylık, Faysal; Mutluer, Ferit Onur; Tosu, Aydın Rodi; Selçuk, Murat

doi:10.1155/2015/305142

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…The anterior mitral valve leaflet in our bicuspid aortic valve cohort measured statistically significantly longer when compared with the control group ( P < 0.001). This was in keeping with our visual impression as well as supporting the findings of a previous smaller study ( 10 ). In our cohort, none of the patients had systolic anterior motion of this abnormally long anterior mitral valve leaflet, and therefore no functional implications of this abnormality were noted.…”

Section: Discussionsupporting

confidence: 93%

“…However, several studies have shown what appears to be more than a coincidental link between bicuspid aortic valve and mitral valve prolapse ( 6 , 7 , 8 ) with an incidence as high as 5% reported in this setting by Schaeffer and coworkers ( 9 ). An association with rare congenital abnormalities of the mitral valve has been suggested, including a case report of a double orifice mitral valve in the setting of a bicuspid aortic valve ( 10 ). Minor structural abnormalities of the mitral valve in the setting of BAVs have also been reported with one small study showing an association with an abnormal anterior mitral valve leaflet ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

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A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves

Rensburg¹,

Herbst²,

Doubell³

2017

Echo Research and Practice

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The therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-up of the mitral valve. A retrospective analysis of echocardiograms done at a referral hospital over five years was conducted in patients with bicuspid aortic valves with special attention to congenital abnormalities of the mitral valve. One hundred and forty patients with a bicuspid aortic valve were included. A congenital mitral valve abnormality was present in eight (5.7%, P = 0.01) with a parachute mitral valve in four (2.8%), an accessory mitral valve leaflet in one (0.7%), mitral valve prolapse in one, a cleft in one and the novel finding of a trileaflet mitral valve in one. Minor abnormalities included an elongated anterior mitral valve leaflet (P < 0.001), the increased incidence of physiological mitral regurgitation (P < 0.001), abnormal papillary muscles (P = 0.002) and an additional chord or tendon in the left ventricle cavity (P = 0.007). Mitral valve abnormalities occur more commonly in patients with bicuspid aortic valves than matched healthy individuals. The study confirms that abnormalities in these patients extend beyond the aorta. These abnormalities did not have a significant functional effect.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves

Rensburg¹,

Herbst²,

Doubell³

2017

Echo Research and Practice

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“…In addition to the biomechanical properties of the valve, signaling pathways that regulate migration and differentiation of cellular components are thought to be responsible for the embryogenesis and pathogenesis of acquired valve diseases. It was reported that some genes involved in mitral and Open Journal of Veterinary Medicine aortic valve pathogenesis regulate general differentiation and morphogenesis of all valves [4]. For example, NOTCH-1 signaling involved in the pathogenesis of aortic valve disease has been shown to play important roles in normal valvulogenesis of all valves, by regulating the activity of various other genes and transcription factors [5].…”

Section: Case Presentationmentioning

confidence: 99%

Anterior Mitral Valve Orifice in a Dog

Sayilkan¹,

Yücel²,

Küllük³

et al. 2021

OJVM

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The patient was admitted to OndokuzMayıs University Animal Hospital Internal Medicine outpatient clinic with complaints of epileptic seizures and hypothyroidism. A description of the patient's owner is available in the history information. There was no physician information. Bradycardia was found in the electrocardiography of the patient. 2-D, M-Mode, PW, CW and Color doppler examinations were performed. Left-ventricular hypokinetic and mitral and tricuspidal valve movements were observed with limited M-Mode imaging. Anterior mitral orifice of 2 mm width was detected on septal mitral valve by PW doppler and color doppler. With this orifice, the presence of regurgitant jet, which covers LA at a rate of 1/3 and was 3.2 m/sec, together with mitral regurgitation (0.5 m/sec.), was demonstrated. PISA calculations; VFR (mL/s), ERO (mm 2 ) and RVol (mL/pulse) values were calculated as if there were mitral regurgitation and data were obtained for mild-moderate mitral regurgitation. Therefore, no operative treatment of the orifice was recommended. Mitral valve orifice is a rare pathology and this is the first report in canine veterinary practice with degenerative mitral valve disorder. We aimed to underline the possibility of mitral orifice development in degenerative mitral valve disorders, known to present with vegetations and varying degrees of prolapsus, conventionally.

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Transesophageal Echocardiographic Evaluation of a Double Orifice Mitral Valve

Fernando

Williamson

Díaz

et al. 2019

Journal of Cardiothoracic and Vascular Anesthesia

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Intraoperative transesophageal echocardiography currently is used routinely for many cardiothoracic surgical procedures. Although it is often used for intraoperative cardiac monitoring and to confirm preoperative echocardiographic findings, it may sometimes result in the discovery of unexpected pathology. In this e-challenge, a patient was found to have a mitral valve abnormality that was not previously detected on the preoperative transthoracic echocardiogram. The mitral valve anomaly subsequently was evaluated to characterize the anatomy, interrogate the valve, and provide a diagnosis.

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Double Orifice Mitral Valve and Bicuspid Aortic Valve: Pieces of the Same Single Puzzle?

Cited by 4 publications

References 5 publications

A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves

A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves

Anterior Mitral Valve Orifice in a Dog

Transesophageal Echocardiographic Evaluation of a Double Orifice Mitral Valve

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