2023
DOI: 10.21203/rs.3.rs-2890631/v1
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Down-regulation CD36 increased proliferation of endothelial cell in hypertrophic cardiomyopathy

Abstract: Background: Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease caused by genetic mutations. HCM with normal epicardial coronary arteries often reveal microvascular rarefaction and myocardial ischemia.Cluster of differentiation 36 (CD36) is a multifunctional pattern recognition membrane receptor that is highly expressed on microvascular endothelial cells (MVEC) and plays an essential role in endothelial cell function. However,whether CD36 affects vascular endothelial cell proliferation in HCM is uncl… Show more

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