Doxycycline: a new treatment option for COVID-19

COVID-19 prophylaxis with doxycycline and zinc in health care workers: a prospective, randomized, double-blind clinical trial

“…Researchers have suggested that Doxycycline may delay COVID-19 progression via antiinflammatory activities, including viruses that regulate the NF-ƙB pathway (nuclear factor kappa light chain enhancer of activated B cells) and inhibit of proinflammatory cytokine levels (IL-6, IL-1β, TNFα), during acute respiratory distress syndrome (ARDS) in severely ill COVID-19 patients (Anwar et al, 2020). Earlier studies demonstrated the effectiveness of chemically modified tetracyclines against SARS, preventing septic shock and ARDS development (Griffin et al, 2010).In addition, several case reports suggest beneficial effects of Doxycycline preventive treatment.…”