Draft Genome Sequence of Corynebacterium striatum 1961 BR-RJ/09, a Multidrug-Susceptible Strain Isolated from the Urine of a Hospitalized 37-Year-Old Female Patient

Abstract

Corynebacterium striatum commonly colonizes the normal skin and nasopharyngeal tract of humans; however, this potentially pathogenic bacterium has been identified as the causative agent of several nosocomial infections. The current study describes the draft genome of strain 1961 BR-RJ/09, isolated from the urine of a hospitalized patient from Brazil.

When Good Bugs Go Bad: Epidemiology and Antimicrobial Resistance Profiles of Corynebacterium striatum, an Emerging Multidrug-Resistant, Opportunistic Pathogen

“…Similar to other skin flora, the majority of the described infections have been limited to isolated bacteremia, central line infections, and occasionally, endocarditis (7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Over recent years, the scope of these infections has broadened to include respiratory, wound, medical hardware/devices, and even urinary tract infections (16)(17)(18)(19)(20)(21)(22)(23). While the reasons for this increased association with multiple pathological processes may not be entirely apparent, a likely contributing factor is the increased ease and accuracy of the identification of Corynebacterium spp., including C. striatum, from clinical cultures (24,25).…”

Efficient differentiation of Corynebacterium striatum , Corynebacterium amycolatum and Corynebacterium xerosis clinical isolates by multiplex PCR using novel species-specific primers

“…Herein, we have developed a multiplex PCR method based on species-distinctive genes for accurate identification at the species level of C. striatum, C. amycolatum and C. xerosis. Speciesspecific target genes were detected by whole-genome comparisons between recently sequenced isolates (Pacheco et al, 2015;Mattos-Guaraldi et al, 2015). In brief, comparative genome analyses were performed through the software platforms EDGAR 2.0 (http://edgar.computational.bio) and SEED Viewer (http://pubseed.theseed.org); hypothetical genes were filtered out and the remaining annotated unique genes for each species were further interrogated using NCBI's BlastN searches for definition of PCR targets.…”

Corynebacterium striatum thrombophlebitis: a nosocomial multidrug-resistant disease?

“…C. striatum is now increasingly implicated in nosocomial sepsis, frequently associated with medical devices [3,9]. Furthermore, the development of antibiotic resistance among C. striatum, especially to daptomycin, is alarming [1][2][3][4][5][6][7][8][9][10][11][12][13].…”

“…Furthermore, the development of antibiotic resistance among C. striatum , especially to daptomycin, is alarming [1–13].…”

“…Corynebacterium striatum is a Gram-positive rod-shaped bacterium that is a commensal of the skin and respiratory tract with a human pathogenesis that is now recognized [1][2][3]. Although endocarditis is the most frequent clinical form, other severe infections have been reported, such as pleuropulmonary infections, breast and pancreatic abscesses, peritonitis, septic arthritis, osteomyelitis, ventricular device infections and even urinary tract infections [1,[4][5][6][7][8][9][10][11]. C. striatum is now increasingly implicated in nosocomial sepsis, frequently associated with medical devices [3,9].…”