Draft Genome Sequence of Novosphingobium sp. Strain HII-3, a Bacterium Capable of Degrading the Cembranoid α(β)-2,7,11-Cembratriene-4,6-Diol to Farnesal

Huang, Shuxian; Qian, Yumei; Wei, Tao; Jia, Chuanbao; Yang, Pengfei; Mao, Duobin

doi:10.1128/genomea.00136-18

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…Recently, Novosphingobium sp. HII-3, isolated from cured tobacco leaf, was confirmed to degrade the CBT-diol to farnesal [55]. β-CBT-diol was converted into triol compounds CYP450s [56,57], and the chemoenzymatic route to oxyfunctionalised cembranoids was facilitated by substrate and protein engineering [58].…”

Section: Effects Of Biocatalysis On Bioactivities Of Tobacco Cembrmentioning

confidence: 99%

A Review on Bioactivities of Tobacco Cembranoid Diterpenes

Ning

Liu

et al. 2019

Biomolecules

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Cembranoids are carbocyclic diterpenes comprising four isoprene units and are natural products with a parent skeleton consisting of a 14-membered ring. They have gained wide interest in recent years and are a major hotspot in the research of natural product chemistry. Since 1962, various tobacco cembranoid diterpenes have been identified. This review systematically discusses and summarises the excellent antimicrobial, insecticidal, cytotoxic and neuroprotective activities of tobacco cembranoid diterpenes. These compounds show potential to be developed as botanical fungicides, cytotoxic drugs and drugs for the treatment of human immunodeficiency virus, Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. However, there are relatively few studies on the structure–activity relationship (SAR) of tobacco cembranoid diterpenes. Therefore, future studies should focus on their structural modification, SAR and biogenic relationships.

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Section: Effects Of Biocatalysis On Bioactivities Of Tobacco Cembrmentioning

confidence: 99%

A Review on Bioactivities of Tobacco Cembranoid Diterpenes

Ning

Liu

et al. 2019

Biomolecules

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“…Among them, Sphingomonas is a new type of microbial resource which can be used for the biodegradation of aromatic compounds. According to the literature sources, the solanone is transformed into important avor compounds such as norsolandione, solanofuran, solanicacid during aging [41]. The avor enhancer produced by the biotransformation of tobacco cembranoids compounds can be added to the tobacco in fermentation to improve the aroma [9,42].…”

Section: Discussionmentioning

confidence: 99%

Microbial communities changes across aging process of tobacco leaves

Wang

Jin

Zhang

et al. 2022

Preprint

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Background: Microbial communities that inhabit aging tobacco leaves play a key role in improving quality by interactions with themselves and tobacco leaves to release tannins, increase sugar levels, promote aromatic taste and degrade harmful compounds. A better understanding of microbial communities on the aging of tobacco leaves could provide an important microbial repository for the industrial applications. Results: Here, we examined the structural and compositional changes of microbial communities and identified the potential metabolic pathways of bacteria and fungi throughout the aging process. The results showed that the diversity and structure of the microbial communities keep changing along with the aging process went on. The richness and diversity of bacterial community decreased, while the richness of fungal community was in an inverse trend. At the phylum level, the bacterial community was dominated by Proteobacteria, Actinobacteria, Firmicutes, and Bacteroidete, while Ascomycota and Basidiomycota were the dominant species in the fungal community. In the bacterial community, metabolic functions related to the carbon and nitrogen cycles which response to the degradation of harmful components, and the metabolism of aromatic hydrocarbons showed extremely dynamic at different aging periods. The change of the main nutritional mode of the fungal community also led to an increase in the abundance of saprophytic fungi. Conclusion: These results provide information on the succession of microbial community structure and function in the whole process of tobacco aging and suggest that the aging process of tobacco leaves can be a natural microbial collection for target microorganism and their metabolites. It also enables the further investigation of coordination mechanisms between beneficial microbial regulation and pathogenicity during aging process.

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“…Among them, Sphingomonas is a new type of microbial resource which can be used for the biodegradation of aromatic compounds. According to the literature sources, it helped transforming the solanone into important flavor compounds such as norsolandione, solanofuran, solanicacid during aging (Huang et al 2018). The flavor enhancer produced by the biotransformation of tobacco cembranoids compounds can be added to the tobacco in fermentation to improve the aroma quality of tobacco products (El Sayed et al 2008, El Sayed andSylvester 2007).…”

Section: Discussionmentioning

confidence: 99%

The diversity, structure and function of microbial communities changes across aging process of tobacco leaves

Wang

Jin

Chen

et al. 2022

Environ. Res. Commun.

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Microbial communities that inhabit aging tobacco leaves play a key role in improving products quality. A better understanding of microbial communities on the aging of tobacco leaves could provide an important microbial repository for the industrial applications. Here, we examined the structural and compositional changes of microbial communities throughout the aging process of by tobacco leaves 16 S and ITS rRNA amplicon sequencing techniques and identified the potential metabolic pathways of bacteria and fungi using Functional Annotation of Prokaryotic Taxa (FAPROTAX) and Fungi Functional Guild (FUNGuild), respectively. The results showed that the diversity and structure of the microbial communities keep changing along with the aging process went on. The richness and diversity of bacterial community decreased, while the richness of fungal community was in an inverse trend. At the phylum level, the bacterial community was dominated by Proteobacteria, Actinobacteria, and Firmicutes, while Ascomycota and Basidiomycota were the dominant species in the fungal community. In the bacterial community, metabolic functions related to the carbon and nitrogen cycles which response to the degradation of harmful components, and the metabolism of aromatic hydrocarbons showed extremely dynamic at different aging periods. The change of the main nutritional mode of the fungal community also led to an increase in the abundance of saprophytic fungi. These results provide information on the succession of microbial community structure and function in the whole process of tobacco aging and suggest that the aging process of tobacco leaves can be a natural microbial collection for target microorganism and their metabolites. It also enables the further investigation of coordination mechanisms between beneficial microbial regulation and pathogenicity during aging process.

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Draft Genome Sequence of Novosphingobium sp. Strain HII-3, a Bacterium Capable of Degrading the Cembranoid α(β)-2,7,11-Cembratriene-4,6-Diol to Farnesal

Cited by 4 publications

References 10 publications

A Review on Bioactivities of Tobacco Cembranoid Diterpenes

A Review on Bioactivities of Tobacco Cembranoid Diterpenes

Microbial communities changes across aging process of tobacco leaves

The diversity, structure and function of microbial communities changes across aging process of tobacco leaves

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