Draft Genome Sequences of Burkholderia pseudomallei and Staphylococcus aureus, Isolated from a Patient with Chronic Rhinosinusitis

Sidjabat, Hanna E.; Cottrell, Kyra; Cervin, Anders

doi:10.1128/genomea.01075-15

Cited by 6 publications

(6 citation statements)

References 12 publications

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“…Their variations have been seen at the genomic, epigenetic, transcriptomic and proteomic levels. Although genome data for human population from melioidois endemic areas is still scarce, genome data for B.pseudomallei has been accumulating ( Holden et al, 2004 ; Hayden et al, 2012 ; Price et al, 2013 , 2016 ; Sahl et al, 2013 , 2016 ; Daligault et al, 2014 ; Bugrysheva et al, 2015 ; Chen et al, 2015 ; Hsueh et al, 2015 ; Johnson et al, 2015a , b ; McRobb et al, 2015 ; Nandi et al, 2015 ; Sidjabat et al, 2015 ; Song et al, 2015 ; Spring-Pearson et al, 2015 ; Viberg et al, 2015 ; Chapple et al, 2016 ; Aziz et al, 2017 ; Chewapreecha et al, 2017 , 2019 ; Podnecky et al, 2017 ; Viberg et al, 2017 ; Webb et al, 2019 ). When combined with spatial and temporal information, this allows further exploration of allelic variants and a shift in allele frequency over space and time.…”

Section: Discussionmentioning

confidence: 99%

An Evolutionary Arms Race Between Burkholderia pseudomallei and Host Immune System: What Do We Know?

et al. 2021

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A better understanding of co-evolution between pathogens and hosts holds promise for better prevention and control strategies. This review will explore the interactions between Burkholderia pseudomallei, an environmental and opportunistic pathogen, and the human host immune system. B. pseudomallei causes “Melioidosis,” a rapidly fatal tropical infectious disease predicted to affect 165,000 cases annually worldwide, of which 89,000 are fatal. Genetic heterogeneities were reported in both B. pseudomallei and human host population, some of which may, at least in part, contribute to inter-individual differences in disease susceptibility. Here, we review (i) a multi-host—pathogen characteristic of the interaction; (ii) selection pressures acting on B. pseudomallei and human genomes with the former being driven by bacterial adaptation across ranges of ecological niches while the latter are driven by human encounter of broad ranges of pathogens; (iii) the mechanisms that generate genetic diversity in bacterial and host population particularly in sequences encoding proteins functioning in host—pathogen interaction; (iv) reported genetic and structural variations of proteins or molecules observed in B. pseudomallei—human host interactions and their implications in infection outcomes. Together, these predict bacterial and host evolutionary trajectory which continues to generate genetic diversity in bacterium and operates host immune selection at the molecular level.

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Section: Discussionmentioning

confidence: 99%

An Evolutionary Arms Race Between Burkholderia pseudomallei and Host Immune System: What Do We Know?

et al. 2021

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“…was then confirmed as B pseudomallei with sequence type 1361. It is important to note that sequence type 1361 has not been found in other patients 9 . This was a case of B pseudomallei with a unique sequence type that was not isolated from a melioidosis endemic area.…”

Section: Case Reportmentioning

confidence: 86%

“…Both burkholderia spp. and S aureus were whole genome sequenced using a HiSeq ™ 2000 sequencing system 9 . The burkholderia spp.…”

Section: Case Reportmentioning

confidence: 99%

Melioidosis in a patient with chronic rhinosinusitis

Phillips¹,

Cervin

Earnshaw

et al. 2016

J. Laryngol. Otol.

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“…The global B. pseudomallei collections 12,13,15,27,[50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65] and newly sequenced data used in this study are divided into a discovery dataset (1,136 isolates) and a validation dataset (875 isolates) (Extended Data Fig 1a & b). Their accession numbers are tabulated in Supplementary table 1.…”

Section: Whole-genome Sequencing Collections Mapping and Annotationmentioning

confidence: 99%

Co-evolutionary signals fromBurkholderia pseudomalleigenomics identify its survival strategies and highlight improving environmental health as prevention policy

Chewapreecha

Pensar

Chattagul

et al. 2020

Preprint

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The soil bacterium Burkholderia pseudomallei is the causative agent of melioidosis and a significant cause of human morbidity and mortality in many tropical and sub-tropical countries. The species notoriously survives harsh environmental conditions but the genetic architecture for these adaptations remains unclear. Here we employed a powerful combination of genome-wide epistasis and co-selection studies, gene expression analysis, and gene knockout assays to uncover genetic markers that have been repeatedly selected through B. pseudomallei evolution. These enabled us to identify a large number of mutation pairs under co-selection in distinct genes and non-coding RNA, of which a majority (61.5%) of signals detected in the discovery dataset can be replicated in the validation dataset (totalling 2,011 genomes). Genes under co-selection are mostly conditionally expressed with marked expression correlation of gene-gene pairs found in physical stress conditions. We discovered a putative adhesin (BPSL1661) as a hub of co-selection signals and experimentally confirmed the essential role of BPSL1661 under nutrient deprivation. The gene co-selection network surrounding BPSL1661 likely offers B. pseudomallei a selective advantage to survive nutrient limited conditions. We propose that anthropogenic activities such as pre- and post-harvest crop residue burning have accelerated soil nutrient depletion and may have directly contributed to the preferential survival of B. pseudomallei over benign soil microorganisms. This is expected to lead to a consequent increase in the incidence of melioidosis should the slash-and-burn practices continue to expand.

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Draft Genome Sequences of Burkholderia pseudomallei and Staphylococcus aureus, Isolated from a Patient with Chronic Rhinosinusitis

Cited by 6 publications

References 12 publications

An Evolutionary Arms Race Between Burkholderia pseudomallei and Host Immune System: What Do We Know?

An Evolutionary Arms Race Between Burkholderia pseudomallei and Host Immune System: What Do We Know?

Melioidosis in a patient with chronic rhinosinusitis

Co-evolutionary signals fromBurkholderia pseudomalleigenomics identify its survival strategies and highlight improving environmental health as prevention policy

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