Dramatic shortening of the diagnosis of multidrug-resistant tuberculosis by the detection of rifampicin resistance using a genotypic method: GeneXpert MTB/RIF assay

Rakha, Ehab; Elshahawy, Heba

doi:10.1007/s00580-017-2631-z

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…With minimum biohazards, Gene Xpert ® MTB/RIF was found better in the assessment of DST. Due to its ability to shorten the diagnosis of MDR-TB to just 2 h, instead of weeks, it takes on the conventional methods [ 112 ]. In this respect, a study from Kosovo found GeneXpert to be able to detect additional cases of TB compared to LJ culturing and smear microscopy.…”

Section: Impact Of Treatment Optionsmentioning

confidence: 99%

A Saudi Arabian Public Health Perspective of Tuberculosis

Saati

Khurram

Faidah

et al. 2021

IJERPH

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Tuberculosis is a global health challenge due to its spreading potential. The Kingdom of Saudi Arabia (KSA) faces a challenge in the spread of tuberculosis from migrant workers, but the foremost threat is the huge number of pilgrims who travel to visit sacred sites of the Islamic world located in the holy cities of Makkah and Al Madina. Pilgrims visit throughout the year but especially in the months of Ramadan and Zul-Hijah. The rise of resistance in Mycobacterium tuberculosis is an established global phenomenon that makes such large congregations likely hotspots in the dissemination and spread of disease at a global level. Although very stringent and effective measures exist, the threat remains due to the ever-changing dynamics of this highly pathogenic disease. This overview primarily highlights the current public health challenges posed by this disease to the Saudi health system, which needs to be highlighted not only to the concerned authorities of KSA, but also to the concerned global quarters since the pilgrims and migrants come from all parts of the world with a majority coming from high tuberculosis-burdened countries.

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Section: Impact Of Treatment Optionsmentioning

confidence: 99%

A Saudi Arabian Public Health Perspective of Tuberculosis

Saati

Khurram

Faidah

et al. 2021

IJERPH

View full text Add to dashboard Cite

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“…Earlier reported GeneXpert sensitivity variations ranged from 57% to 96% for negative AFB samples [19][20][21][22]. The difference in patient selection criteria between trials that would involve only investigation of strong suspects of TB patients can explain different sensitivities [23].…”

Section: Discussionmentioning

confidence: 99%