2021
DOI: 10.3390/separations8090145
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Dried Blood Spot in Toxicology: Current Knowledge

Abstract: Dried Blood Spot (DBS) is becoming very popular in various medical fields, especially in toxicology. Nowadays it is commonly used in newborn screening for inherited or congenital diseases. This paperwork is based on a review of available literature. DBS is simple and rapid, it does not require trained medical staff to collect the samples. Specimens can be easily and safely transported to the laboratory. DBS provides an opportunity for roadside testing and rather quick results. Venous blood spot, collected from… Show more

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Cited by 3 publications
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“…The first use of dried blood microsamples was reported in 1961, when a neonatal screening for metabolic diseases was developed (Guthrie, 1961). The interest increased rapidly, and besides clinical diagnostics, applications in the field of drug‐of‐abuse testing followed (Henion et al, 2013; Lehmann et al, 2013; Lim, 2018; Niemiec, 2021). The potential of dried blood spots (DBS) as a complementary matrix for anti‐doping controls was discovered about two decades ago (Peng et al, 2000), leading to further studies and investigations targeting various groups of prohibited substances and methods (Thevis, 2021; Thevis et al, 2022; Thomas et al, 2011, 2012; Yuan et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
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“…The first use of dried blood microsamples was reported in 1961, when a neonatal screening for metabolic diseases was developed (Guthrie, 1961). The interest increased rapidly, and besides clinical diagnostics, applications in the field of drug‐of‐abuse testing followed (Henion et al, 2013; Lehmann et al, 2013; Lim, 2018; Niemiec, 2021). The potential of dried blood spots (DBS) as a complementary matrix for anti‐doping controls was discovered about two decades ago (Peng et al, 2000), leading to further studies and investigations targeting various groups of prohibited substances and methods (Thevis, 2021; Thevis et al, 2022; Thomas et al, 2011, 2012; Yuan et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…The first use of dried blood microsamples was reported in 1961, when a neonatal screening for metabolic diseases was developed (Guthrie, 1961). The interest increased rapidly, and besides clinical diagnostics, applications in the field of drug-of-abuse testing followed (Henion et al, 2013;Lehmann et al, 2013;Lim, 2018;Niemiec, 2021).…”
Section: Introductionmentioning
confidence: 99%