2022
DOI: 10.1007/s12024-021-00434-5
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Dried matrix spots: an evolving trend in the toxicological field

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Cited by 11 publications
(6 citation statements)
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References 65 publications
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“…12,13 Dried samples are also suitable for analysis of drugs of abuse. 7,14,15 Several devices are available to collect and ship dried matrix spots; some of them are designed to collect defined sample volumes. These devices might be too expensive for use in resource-limited settings.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…12,13 Dried samples are also suitable for analysis of drugs of abuse. 7,14,15 Several devices are available to collect and ship dried matrix spots; some of them are designed to collect defined sample volumes. These devices might be too expensive for use in resource-limited settings.…”
Section: Introductionmentioning
confidence: 99%
“…Dried blood or plasma spots have been used in epidemiological studies in LMICs, for example, in studies of infectious diseases 6,10,11 and in therapeutic drug monitoring 12,13 . Dried samples are also suitable for analysis of drugs of abuse 7,14,15 …”
Section: Introductionmentioning
confidence: 99%
“…Today DBS technology is not limited to whole blood as primarily assayed biofluid and includes much wider range of utilised dried body fluids such as urine, saliva, milk etc. The general term used for air-dried biosamples on filter paper is Dried Matrix Spots (DMS) (Jacques et al 2022 ). DBS technology minimizes invasiveness of blood sampling, reduces animal mortality in preclinical studies.…”
Section: Introductionmentioning
confidence: 99%
“…Adicionalmente, a necessidade crescente da utilização de abordagens alternativas para obtenção de amostras clínicas de menor volume, com menor risco, maior aproveitamento e de forma menos invasivas, vem sendo discutido na literatura para aplicação no monitoramento terapêutico e para ampliação de acesso ao TDM, um recurso importante no cuidado aos pacientes (Jacques et al, 2022;Trifonova et al, 2019).…”
Section: Quantificação De Fármacos Por Cromatografia Líquidaunclassified
“…Novas estratégias alternativas de amostragem têm sido introduzidas cada vez mais no campo do monitoramento terapêutico de medicamentos para várias classes de medicamentos e têm sido relatadas como uma solução para superar as limitações da amostragem convencional, trazendo vários benefícios (Jacques et al, 2022;Trifonova et al, 2019). Um desses dispositivos de microamostragem, o dispositivo de amostragem de plasma seco (DPS), consiste em um volume de plasma seco em um papel filtro disponível comercialmente em formato de cartão.…”
Section: Abordagens Alternativas De Obtenção De Amostras Clínicas Par...unclassified