ABSTRACT. Objective: Given the recent downturn in the U.S. economy, we considered in this study the processes linking economic stressors, psychological distress, and two alcohol-related outcomes (past-month drinking and problematic drinking). Method: Data were drawn from a mail survey of a national sample of 663 respondents. Structural equation modeling was used to assess whether psychological distress mediates the associations between economic stressors and the alcohol-related outcomes considered and whether these associations varied by gender. Results: Controlling for correlations among the outcomes and the effects of the sociodemographic control variables, psychological distress was found to partly explain the association between economic stressors and problematic drinking. The mediating effects on problematic drinking were signifi cantly greater for men than women. Conclusions: The fi ndings demonstrate the utility of considering interrelationships among alcohol-related outcomes and, in this context, reveal the circumstances in which gender matters most for understanding the associations among economy-related stressors, psychological distress, and drinking. (J. Stud. Alcohol Drugs, 73, 811-819, 2012) Received: January 17, 2012. Revision: May 17, 2012. This research was funded by National Institute on Alcohol Abuse and Alcoholism (NIAAA) grant R01AA017202 to Judith A. Richman. The article's contents are solely the responsibility of the authors and do not necessarily represent the offi cial views of NIAAA.*Correspondence may be sent to Robyn Lewis Brown at DePaul University, Department of Sociology, 990 West Fullerton Ave., Suite 1100, Chicago, IL 60614, or via email at: rbrown50@depaul.edu. economic circumstances and their consequences. This is consistent with the tendency of stress research, more generally, to focus on individual-level stressors and overlook potential linkages between broader social forces and personal hardship (Galea, 2007;Richman et al., 2008; Turner and Lloyd, 2005).Addressing this limitation, the present study applies a broader defi nition of economy-related strain that includes diminished quality of and compensation from employment (e.g., decreased hours, furloughs, lack of merit raises, increased responsibilities at work resulting from the layoffs of other workers, and not obtaining jobs congruent with one's education and skill level), home ownership problems and undesirable living conditions, lack of access to or inability to afford health care, social role constraints, unemployment, and underemployment. We examined how such strains infl uence psychological distress and alcoholrelated outcomes, applying a tension-reduction or selfmedication model of drinking. This perspective maintains that alcohol is often used to cope with psychological distress, as well as the stressful life experiences that elicit distress (Richman et al., 1997(Richman et al., , 2002Steele and Josephs, 1990).Additionally, because men are consistently found to drink more than women and experience more alcohol-...