Drone inflight mixing of biochemical samples

Katariya, Mayur; Chung, Dwayne Chung Kim; Minife, Tristan; Gupta, Harshit; Zahidi, Alifa Afiah Ahmad; Liew, Oi Wah; Ng, Tuck Wah

doi:10.1016/j.ab.2018.01.004

Cited by 16 publications

(7 citation statements)

References 22 publications

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“…The integration of unmanned aerial vehicles (UAVs), also known as drones, into health systems represents an area of massive potential [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. Half the world population lives in rural areas, defined in diverse ways across countries, but characterized by non-urban density population [19,20].…”

Section: Introductionmentioning

confidence: 99%

Context-Specific Challenges, Opportunities, and Ethics of Drones for Healthcare Delivery in the Eyes of Program Managers and Field Staff: A Multi-Site Qualitative Study

Jeyabalan

Nouvet

Meier³

et al. 2020

Drones

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Unmanned aerial vehicles (UAVs), also known as drones, have significant potential in the healthcare field. Ethical and practical concerns, challenges, and complexities of using drones for specific and diverse healthcare purposes have been minimally explored to date. This paper aims to document and advance awareness of diverse context-specific concerns, challenges, and complexities encountered by individuals working on the front lines of drones for health. It draws on original qualitative research and data from semi-structured interviews (N = 16) with drones for health program managers and field staff in nine countries. Directed thematic analysis was used to analyze interviews and identify key ethical and practical concerns, challenges, and complexities experienced by participants in their work with drones for health projects. While some concerns, challenges, and complexities described by study participants were more technical in nature, for example, those related to drone technology and approval processes, the majority were not. The bulk of context-specific concerns and challenges identified by participants, we propose, could be mitigated through community engagement initiatives.

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Section: Introductionmentioning

confidence: 99%

Context-Specific Challenges, Opportunities, and Ethics of Drones for Healthcare Delivery in the Eyes of Program Managers and Field Staff: A Multi-Site Qualitative Study

Jeyabalan

Nouvet

Meier³

et al. 2020

Drones

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show abstract

“…Drones can potentially overcome the logistic challenges as they are not subjected to traffic delays [13], and most importantly, they are able to reach regions that lack adequate roads faster. However, for delivery of fragile medications, blood [14] and diagnostic clinical laboratory specimens [15][16][17], drones are practical only if the quality of transported products is not adversely affected. Thus, drones as a novel method for medicine transportation, must be tested to determine their impact on medicine quality.…”

Section: Introductionmentioning

confidence: 99%

An Evaluation of the Delivery of Medicines Using Drones

Hii

Courtney²,

Royall

2019

Drones

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This study tests the impact of drone transportation on the quality of a medicine. Modelling the critical process parameters of drone flight, the effects of temperature and vibration on insulin were investigated using the pharmacopoeia methods. The medicine, Actrapid, (3.5 mg/mL of insulin), was flown by a quad-rotor drone. Insulin stored between −20 and 40 °C for 30 mins, and subjected to vibration (0–40 Hz, 25 °C, 30 mins) passed the pharmacopeia tests. Dynamic light scattering identified the active tetrameric and hexameric forms of insulin post testing. Vibration frequencies during drone flight were between 0.1 and 3.4 Hz. There was no evidence of visible insulin aggregates following the drone transportation. The differences in UV absorbance readings between flown Actrapid and controls were insignificant (p = 0.89). No adverse impact of drone transport on insulin was observed. This study provides supporting evidence that drone transportation of medicinal products containing insulin is feasible. The authors recommend that when considering the drone delivery of medicines five tests need to be applied. These tests must determine the safe flight time and range, the quality of the medicine post flight, the onboard conditions experienced by the medicine, the security of the drone supply chain and the effect of drone failure on both the medicine and the environment.

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“…Recent advances in the drone (unmanned aerial vehicles, or UAV) technology allow one to perform unmanned delivery-to-the-door of various goods [19]. Drones succeed with blood transportation [20][21][22][23][24] (and even organ transportation is being explored [25]), implying that transporting by drones the less sensitive [12] COVID-19 test samples (e.g, upper respiratory specimens in nasopharyngeal and oropharyngeal swab or lower respiratory specimens like sputum) may also be technically feasible [26] (related studies went so far as to explore testing for avian influenza A (H7N9) virus directly on the drone [27]). This opens the potential to use drones for mass-testing the population for COVID-19, most importantly-including asymptomatic people: it has been reported that symptomless people can be infectious as well [1][2][3]5] (in fact, since symptomatic people were advised to isolate very early, it may be the case that the pandemic occurred mostly due to asymptomatic transmission [4]).…”

Section: Resultsmentioning

confidence: 99%

Modeling quarantine during epidemics and mass-testing using drones

2020

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We extend the classical SIR epidemic spread model by introducing the "quarantined" compartment. We solve (numerically) the differential equations that govern the extended model and quantify how quarantining "flattens the curve" for the proportion of infected population over time. Furthermore, we explore the potential of using drones to deliver tests, enabling mass-testing for the infection; we give a method to estimate the drone fleet needed to deliver the tests in a metropolitan area. Application of our models to COVID-19 spread in Sweden shows how the proposed methods could substantially decrease the peak number of infected people, almost without increasing the duration of the epidemic.

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Drone inflight mixing of biochemical samples

Cited by 16 publications

References 22 publications

Context-Specific Challenges, Opportunities, and Ethics of Drones for Healthcare Delivery in the Eyes of Program Managers and Field Staff: A Multi-Site Qualitative Study

Context-Specific Challenges, Opportunities, and Ethics of Drones for Healthcare Delivery in the Eyes of Program Managers and Field Staff: A Multi-Site Qualitative Study

An Evaluation of the Delivery of Medicines Using Drones

Modeling quarantine during epidemics and mass-testing using drones

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