Drosophilasmall ovarygene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatin

Abstract

Summary statement:Small ovary maintains the integrity of the stem cell niche by regulating piRNA-mediated transposon silencing acting as a key component of the heterochromatin.All rights reserved. No reuse allowed without permission.was not peer-reviewed) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.The copyright holder for this preprint (which . http://dx.doi.org/10.1101/383265 doi: bioRxiv preprint first posted online Aug. 2, 2018; 2 AbstractSelf-renewal and differentiation of stem cells is one of the fundamental biological phenomena relying on proper chromatin organisation. In our study, we describe a novel chromatin regulator encoded by the Drosophila small ovary (sov) gene. We demonstrate that sov is was not peer-reviewed) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.