Drosophila model and network pharmacology to explore novel targets and novel active components of chinese traditional medications for treating kidney stones

Gastrodin improves osteoblast function and adhesion to titanium surface in a high glucose environment

“…To evaluate the effect of gastrodin (Solaibao, Beijing, China) alone on the viability of MC3T3-E1 cells, we seeded the cells in 96-well plates at 1 × 10 3 cells/well overnight. The experimental groups were treated with 1, 5, 10 and 20 μM of gastrodin for 1 and 3 days [ 15 , 22 , 23 ]. And the glucose concentration is 5.5 mM in α-MEM.…”

Exploring potential targets for quercetin treatment of colorectal cancer through network pharmacology and molecular docking technology

“…Network pharmacology emphasizes much way of signaling pathways regulate, to improve the therapeutic effect of drugs, reduce side effects, so as to improve the success rate of new drug clinical trials, save drug research and development costs. With the rise of network pharmacology, make its are widely applied to explore the traditional Chinese medicine and compound ingredients, targets, such as multiple pathways direction [13][14][15]. Molecular docking is refers to the receptor through energy, space match between matching and form compounds, and chemical properties and predict complex structure and affinity of a theoretical simulation method.…”