Drucker in the Classroom

Cohen, William A.

doi:10.5848/amacom.978-0-814409-54-1_3

Cited by 3 publications

(5 citation statements)

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“…(mg fungal protein)-1 • h-1, which is not high when compared with the activity of some aerobic fungi (e.g. [19]), but is comparable to the most active of proteolytic rumen bacteria and much higher than that of the more numerous rumen bacteria [18].…”

Section: Discussionmentioning

confidence: 78%

Proteolytic activity of a rumen anaerobic fungus

Wallace¹

1985

FEMS Microbiology Letters

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A strain of the anaerobic phycomycetous fungus Neocallimastix frontalis isolated from the rumen of a sheep had a high proteolytic activity which became predominantly extracellular during growth. Proteolytic activity appeared to be due to a metalloprotease, as it was inhibited by 1,10‐phenanthroline, EDTA and other chelators but not by phenylmethylsulphonyl fluoride (PMSF). Inhibition by EDTA was fully reversed by the addition of Zn2+, Ca2+ or Co2+, whereas addition of metal ions in the presence of 1,10‐phenanthroline restored only a little activity. p‐Chloromercuribenzoate (PCMB) was also inhibitory in dialysed supernatant fluid. N‐α‐p‐Tosyl‐l‐lysine chloromethylketone (TLCK) inhibited proteolysis, suggesting that the protease(s) has a trypsin‐like specificity, but benzoylarginine p‐nitroanilide was not hydrolysed. Protease activity has a broad pH profile with a maximum at pH 7.5. Gel fractionation indicated that most of the activity was in a high‐Mr form.

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Section: Discussionmentioning

confidence: 78%

Proteolytic activity of a rumen anaerobic fungus

Wallace¹

1985

FEMS Microbiology Letters

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“…These are categorized into 3 types and well are explained by using examples (Cohen E., 2002) in tabulated form below The use of intravenous (IV) antibiotics for the treatment of serious infections has become common around the world. It is accepted as the standard treatment for many infections including sepsis, meningitis, endocarditis, intra-abdominal infections, pneumonia, and osteomyelitis.…”

Section: Categories Of Antibiotics Used In Outpatient Parenteral Anti...mentioning

confidence: 99%

Outpatient Intravenous Antibiotic Therapy: Reduces economic burden of patients

Altaf¹,

Zl²,

Nagavamsidhar³

et al. 2018

PharmaTutor

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OPAT it is a frequent source of questions and formal infectious diseases consultations. OPAT is always less expensive than inpatient therapy. Financial savings have been found with OPAT when compared with in hospital stays. The use of intravenous (IV) antibiotics for the treatment of serious infections has become common around the world. It is accepted as the standard treatment for many infectious diseases including other chronic infection like sepsis, meningitis, endocarditis etc. The goals of OPAT program are to provide expert care to patients on IV antibiotics, manage side effects and infections, reduces the need for hospital readmissions. The OPAT having a series of program patient care team includes doctors, nurses, and clinical and hospital pharmacists who are skilled in management of infectious diseases. Intravenous therapy outside the hospital, has only recently become possible, with the introduction of new Antibiotics, better catheters for vascular access, and improved infusion devices. Health care professionals have pioneered the development of OPAT and worked together to develop safe and effective programs. The antibiotics used for OPAT care are chosen for safety, effectiveness and ease of administration and money saving. The IV delivery system needed in the home is much simpler than the large, complicated IV pumps you see in the hospital. OPAT allows suitable patients on intravenous (IV) antibiotics to be discharged early from hospital and treated in their home or community setting by a team of specialist nurses.

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“…In various sources, there is information that various famous scientists have mentioned leadership in various forms throughout history. Furthermore, "first, do no harm" principle, which is accepted as one of the fundamental principles of leadership, is considered to be originated from Hippocrates' "primum non nocere" [12].…”

Section: Origin and History Of The Leadershipmentioning

confidence: 99%

“…Xenophon's Cyropaedia is considered to be the first systematic book written on leadership. Moreover, another important work by the same author, Anabasis (The Fall of the Ten Thousand), contains significant information on effective and ethical leadership [12].…”

Section: Origin and History Of The Leadershipmentioning

confidence: 99%