Drug Candidate Discovery: Targeting Bacterial Topoisomerase I Enzymes for Novel Antibiotic Leads

Abstract

This work could not have been done without the help of many people, scientists and non-scientists alike. First, I would like to thank my committee members for sticking with me through the years. Their input was invaluable, and I learned so much from all of them. Secondly, I want to thank my lab mates. Everyone working in Dr. Tse-Dinh's lab was helpful to me in some way, be it with help setting up an experiment, starting a cell culture over the weekend, or just having a friendly face to talk to. To our lab manager Arasu: his guidance keeps this whole lab running. Without him, I am sure we would all have been lost. Next, I would like to thank the FIU Research Initiative for Scientific Enhancement (RISE) fellowship for offering me funding in my last year of graduate work.