Drug Designing, Discovery and Development Techniques

Martis, Elvis A. F.; Somani, Rakesh R.

doi:10.5772/38948

Cited by 2 publications

(1 citation statement)

References 49 publications

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“…Traditional approaches to this rely on laboratorybased experimentation done by an expert scientist or a chemist with a piece of strong domain knowledge. It is a long step-wise activity involving various stages namely: (i) identification of biological targets, (ii) validation of biological targets, (iii) lead structure search, (iv) lead structure optimization, (v) preclinical studies, (vi) clinical trials, and (vii) formulations for clinical studies [7]. The field of computer science and statistics attempt to automate this complex drug development process to reduce development time and cost.…”

Section: Computer Aided Drug Discoverymentioning

confidence: 99%

Applications of Deep Learning in Bioinformatics and Drug Discovery

Kotkondawar,

Sutar,

Kiwelekar

2024

Preprint

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The remarkable progress and growth in the fields of Artificial Intelligence (AI) and Bio-Chemical sciences in recent times have been continuously solving many complex problems. AI has shown a measurable impact in almost all areas of life including healthcare. The exponential growth of data, technologies for efficient storage, retrieval of this huge data, and ever-increasing computational power have given rise to data-driven AI-based approaches like Deep Learning (DL). Productive use of Big Data has been recognized in many phases of drug discovery. The availability of massive biochemical data catalyzed by the fast processing abilities of GPUs is pushing up the huge success of deep learning approaches for some key activities in drug discovery like drug-target interaction or virtual screening. DL techniques have shown the potential to strategically reduce the time and huge cost spent in the drug discovery pipeline. This paper discusses the significance of DL in the context of biochemical Big Data and the drug discovery process.

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Section: Computer Aided Drug Discoverymentioning

confidence: 99%