Drug Excipient Adsorption Technique for the Preparation of Low-Dose Tableting
NIKHITHA K. SHANMUKHAN,
RAMYA G.,
ARUN RADHAKRISHNAN
Abstract:Objective: This study aimed to improve drug mixability and drug uniformity in personalized medicine low-dose tablet by developing a stable, easily mixable, drug-adsorbed filler. Methods: The research involved adsorbing drug onto filler by using three solvents and drug-to-excipient ratios of 1:50 and 1:75. The drug adsorbed fillers, were analyzed for drug content uniformity and flow properties, which are crucial for accurate dosing and manufacturing of low dose tablet. Results: Formulations T1, T2 and T3 showed… Show more
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