Drug-induced constipation

Branch, Rebecca L; Butt, Tehreem F.

doi:10.1097/fad.0b013e32833080d1

Cited by 11 publications

(8 citation statements)

References 33 publications

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“…When considering comorbid conditions, it is possible that medications being used as treatment may be causing, wholly or in part, the constipation. This could certainly be the case in conditions such as depression, musculoskeletal disorders and cardiovascular diseases where constipation is a known side effect of many medications used for treatment[ 87 , 88 ]. Any increased prevalence of constipation with age may be more related to secondary causes such as comorbid conditions and medications[ 91 ].…”

Section: Discussionmentioning

confidence: 99%

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Potential risk factors for constipation in the community

Werth¹,

Christopher²

2021

WJG

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Constipation is a common community health problem. There are many factors that are widely thought to be associated with constipation but real-world evidence of these associations is difficult to locate. These potential risk factors may be categorised as demographic, lifestyle and health-related factors. This review presents the available evidence for each factor by an assessment of quantitative data from cross-sectional studies of community-dwelling adults published over the last 30 years. It appears that there is evidence of an association between constipation and female gender, residential location, physical activity and some health-related factors such as self-rated health, some surgery, certain medical conditions and certain medications. The available evidence for most other factors is either conflicting or insufficient. Therefore, further research is necessary to determine if each factor is truly associated with constipation and whether it can be regarded as a potential risk factor. It is recommended that studies investigating a broad range of factors are conducted in populations in community settings. Multivariate analyses should be performed to account for all possible confounding factors. In this way, valuable evidence can be accumulated for a better understanding of potential risk factors for constipation in the community.

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Section: Discussionmentioning

confidence: 99%

“…Constipation is a common side effect of many drug classes[ 87 , 88 ] but this is not always evident in population-based studies because few have reported concomitant drug use.…”

Section: Health-related Factorsmentioning

confidence: 99%

Potential risk factors for constipation in the community

Werth¹,

Christopher²

2021

WJG

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“…These included medical conditions, medications and level of physical activity as well as socio-demographic data. Medications were considered to have the potential to cause constipation if listed as an adverse effect in published reviews of the subject (Branch & Butt, 2009;Toney, Wallace, Sekhon, & Agrawal, 2008). Medical conditions associated with constipation identified in the literature included conditions affecting the heart, lower gastrointestinal system (e.g.…”

Section: Potential Risk Factors For Constipationmentioning

confidence: 99%

A longitudinal study of constipation and laxative use in a community-dwelling elderly population

Werth¹,

Williams²,

Pont³

2015

Archives of Gerontology and Geriatrics

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“…Constipation is considered a common side effect of several medications such as analgesics, anticholinergics and cation‐containing agents . Phillips et al conducted a study to evaluate the prevalence of diagnosed constipation in long‐term care (LTC) patients, which revealed that approximately 70% of LTC patients had at least one condition that precipitated constipation, and more than 75% of patients had at least one medication that caused it.…”

Section: What Is Known and Objectivementioning

confidence: 99%