Drug Induced Refractory Headache: Clincial Features And Management

Mathew, Ninan T.; Reuveni, Uri

doi:10.1177/03331024870070s648

Cited by 8 publications

(2 citation statements)

References 3 publications

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“…7 This may prompt a significant drop-out of patients in withdrawal therapy, especially during the initial phase. 8,20,21 To increase the treatment compliance of patients during withdrawal therapy, new therapeutic approaches for symptomatic management during this critical period seem to be an important research area.…”

Section: Discussionmentioning

confidence: 99%

“…Despite these increased withdrawal headaches, 45% of the patients were headache-free on day 12-14 and an additional 33% attained >50% reduction in headache severity compared with pretreatment levels. Mathew et al 20 abruptly stopped symptomatic medications without any drug support in a subgroup of CDH patients. After the 12 weeks of follow-up, 58% improvement was obtained in headache severity.…”

Section: Discussionmentioning

confidence: 99%

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Effect of valproic acid on withdrawal therapy in patients with overuse of chronic daily headache medications

Coşkun

Üçler

Cavdar

et al. 2007

Journal of Clinical Neuroscience

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effect of valproic acid on withdrawal therapy in patients with overuse of chronic daily headache medications

Coşkun

Üçler

Cavdar

et al. 2007

Journal of Clinical Neuroscience

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Chronic daily headache: Theory to therapy

Wheeler

1999

Current Review of Pain

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Headaches are among the most frequent symptoms for which Americans seek physician advice and treatment. Although headache may herald a serious underlying organic or psychological illness, it more commonly represents a primary disorder of brain stem nociceptive processing and modulation. Chronic daily headache characteristically develops gradually from episodic tension or migraine-type headaches into a refractory syndrome often associated with medication overuse and disability. Better understanding of the pathophysiology and evolutionary mechanisms involved in the development of chronic headache has led to recommended changes in nosology originally proposed by the International Headache Society (IHS). Recent scientific and clinical observations prompting revised classification have also led to the integration of pathoanatomic models, which explain persistent headache. Strategies for the management of chronic craniofacial pain should emphasize key behavioral and attitudinal changes and avoidance of medication overusage.

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Chronic use of symptomatic headache medications

Korff

Galer

Stang

1995

Pain

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Chronic use of symptomatic headache medication is believed to be a risk factor for drug-induced chronic headache. This study reports the frequency of chronic use of symptomatic headache medications implicated in drug-induced chronic headache among primary-care headache (PCH) patients and identifies predictors of chronic/frequent use. The design uses a 2-year cohort study of a sample of PCH patients in Group Health Cooperative of Puget Sound, a large health maintenance organization in Seattle, WA. Among 779 PCH patients (aged 18-74 years) interviewed at baseline, 662 (85%) completed both 1- and 2-year follow-up interviews. This study estimates the percent of PCH patients reporting: (1) frequent use of over-the-counter, non-steroidal anti-inflammatory, opioid, sedative-hypnotic, and ergot medications (defined as 14 or more days of use for each class in the prior month), (2) chronic/frequent use of these medications, defined as surpassing criteria for frequent use on at least 2 of the 3 study interviews, and (3) chronic/frequent polypharmacy, defined as chronic/frequent use of 2 or more classes of headache medication. Twenty-one percent of PCH patients were chronic/frequent users of symptomatic headache medications, while 2.6% met study criteria for chronic/frequent polypharmacy. Chronic/frequent use of over-the-counter medications (15.9%) was twice as common as chronic/frequent use of prescription medications (7.7%). Headache days at baseline was the strongest predictor of chronic/frequent medication use. After controlling for baseline persistence and severity, older patients were more likely to be chronic/frequent users of headache medications. The age effect was explained by chronic/frequent use of over-the-counter medications.(ABSTRACT TRUNCATED AT 250 WORDS)

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Drug Induced Refractory Headache: Clincial Features And Management

Cited by 8 publications

References 3 publications

Effect of valproic acid on withdrawal therapy in patients with overuse of chronic daily headache medications

Effect of valproic acid on withdrawal therapy in patients with overuse of chronic daily headache medications

Chronic daily headache: Theory to therapy

Chronic use of symptomatic headache medications

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