Drug-Induced Rhinitis: Narrative Review

Alromaih, Saud; Alsagaf, Lamya; Aloraini, Nouf Mohammad; Al-Rasheed, Abdulaziz; Alroqi, Ahmad; Aloulah, Mohammad; Alsaleh, Saad; Alhawassi, Tariq M.

doi:10.1177/01455613221141214

Cited by 8 publications

(5 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Non-allergic rhinitis is more common in women than in men. It can occur in rhinitis induced by pregnancy, menstruation, and oral contraceptive use [41]. As for allergic rhinitis, when children (age 0-10 years), the incidence of allergic rhinitis is higher in boys than girls.…”

Section: Resultsmentioning

confidence: 99%

Relationship between Degrees of Nasal Obstruction and Obstructive Sleep Apnea

Marlina

Hendrika

Adinda

2023

JOCAMR

View full text Add to dashboard Cite

Obstructive sleep apnea (OSA) is a sleep-related breathing disorder caused by repeated upper airway obstruction. In OSA patients, 46.5%-58% reported having symptoms of hypersomnolence or excessive daytime sleepiness, and it was the most common symptom. Nasal obstruction is considered a risk factor for sleeping and breathing problems and a common problem in OSA sufferers. Nasal obstruction in the general population can reach 30-40% and is a problem that is often consulted in primary or secondary health services. This study aimed to determine the relationship between the degree of nasal obstruction and OSA in students of the Faculty of Medicine, Indonesian Christian University, Class of 2018-2020. This study uses an analytic observation method with a cross-sectional approach. The number of samples of 74 people was obtained by purposive sampling technique. Respondents who met the criteria were assessed for the degree of nasal obstruction using the NOSE scale questionnaire, while OSA was assessed using the ESS questionnaire, and then the data were analyzed using the Chi-Square Test. The results of the Chi-Square statistical test obtained p value = 0.041. So it was concluded that there was a significant relationship between the degree of nasal obstruction and OSA in students of the Faculty of Medicine, Indonesian Christian University Class of 2018-2020.

show abstract

Section: Resultsmentioning

confidence: 99%

Relationship between Degrees of Nasal Obstruction and Obstructive Sleep Apnea

Marlina

Hendrika

Adinda

2023

JOCAMR

View full text Add to dashboard Cite

show abstract

“…Infectious rhinitis is primarily caused by viral upper respiratory tract infections such as rhinoviruses, coronaviruses, and influenza viruses. Medication-induced rhinitis is a known adverse effect of several types of medications, including nonsteroidal anti-inflammatory agents, antihypertensives (β-blockers and calcium channel blockers), and estrogen-containing oral contraceptives . The mechanisms of drug-induced rhinitis are poorly defined, but are understood to involve vasodilation through neurogenic pathways …”

Section: Discussionmentioning

confidence: 99%

“…3,17,22 The mechanisms of drug-induced rhinitis are poorly defined, but are understood to involve vasodilation through neurogenic pathways. 22…”

Section: Differential Diagnosismentioning

confidence: 99%

Allergic Rhinitis

Bernstein,

Makol

et al. 2024

JAMA

View full text Add to dashboard Cite

ImportanceAllergic rhinitis affects an estimated 15% of the US population (approximately 50 million individuals) and is associated with the presence of asthma, eczema, chronic or recurrent sinusitis, cough, and both tension and migraine headaches.ObservationsAllergic rhinitis occurs when disruption of the epithelial barrier allows allergens to penetrate the mucosal epithelium of nasal passages, inducing a T-helper type 2 inflammatory response and production of allergen-specific IgE. Allergic rhinitis typically presents with symptoms of nasal congestion, rhinorrhea, postnasal drainage, sneezing, and itching of the eyes, nose, and throat. In an international study, the most common symptoms of allergic rhinitis were rhinorrhea (90.38%) and nasal congestion (94.23%). Patients with nonallergic rhinitis present primarily with nasal congestion and postnasal drainage frequently associated with sinus pressure, ear plugging, muffled sounds and pain, and eustachian tube dysfunction that is less responsive to nasal corticosteroids. Patients with seasonal allergic rhinitis typically have physical examination findings of edematous and pale turbinates. Patients with perennial allergic rhinitis typically have erythematous and inflamed turbinates with serous secretions that appear similar to other forms of chronic rhinitis at physical examination. Patients with nonallergic rhinitis have negative test results for specific IgE aeroallergens. Intermittent allergic rhinitis is defined as symptoms occurring less than 4 consecutive days/week or less than 4 consecutive weeks/year. Persistent allergic rhinitis is defined as symptoms occurring more often than 4 consecutive days/week and for more than 4 consecutive weeks/year. Patients with allergic rhinitis should avoid inciting allergens. In addition, first-line treatment for mild intermittent or mild persistent allergic rhinitis may include a second-generation H1 antihistamine (eg, cetirizine, fexofenadine, desloratadine, loratadine) or an intranasal antihistamine (eg, azelastine, olopatadine), whereas patients with persistent moderate to severe allergic rhinitis should be treated initially with an intranasal corticosteroid (eg, fluticasone, triamcinolone, budesonide, mometasone) either alone or in combination with an intranasal antihistamine. In contrast, first-line therapy for patients with nonallergic rhinitis consists of an intranasal antihistamine as monotherapy or in combination with an intranasal corticosteroid.Conclusions and RelevanceAllergic rhinitis is associated with symptoms of nasal congestion, sneezing, and itching of the eyes, nose, and throat. Patients with allergic rhinitis should be instructed to avoid inciting allergens. Therapies include second-generation H1 antihistamines (eg, cetirizine, fexofenadine, desloratadine, loratadine), intranasal antihistamines (eg, azelastine, olopatadine), and intranasal corticosteroids (eg, fluticasone, triamcinolone, budesonide, mometasone) and should be selected based on the severity and frequency of symptoms and patient preference.

show abstract

“…Drug-induced rhinitis is associated with a wide variety of drugs including, non-steroidal anti-inflammatory drugs, angiotensin-converting enzyme inhibitors, phosphodiesterase type 5 inhibitors, imidazoline receptor agonists, diuretics, calcium channel blockers, psychotropics, local decongestants and anti-thyroid medication (Alromaih et al., 2022).…”

Section: Differential Diagnosesmentioning

confidence: 99%

Allergic rhinitis

Giri

2023

InnovAiT: Education and inspiration for general practice

View full text Add to dashboard Cite

Allergic rhinitis (AR) is a major public health issue worldwide and one of the top-10 reasons for primary care attendance. AR affects between 10 and 25% of people worldwide, including 10–15% of children and 26% of adults in the United Kingdom. Sneezing, nasal itching, rhinorrhoea, nasal congestion, ocular symptoms (irritation and lacrimation), non-productive cough, Eustachian tube dysfunction and chronic sinusitis are all symptoms of AR. AR can be characterised as seasonal (hay fever), perennial, intermittent, persistent, or occupational, depending on the allergens and the pattern and frequency of symptoms. Asthma and conjunctivitis are significantly associated with AR. A clinical history and physical examination are the most important processes in diagnosis. Skin tests can be used to confirm the diagnosis of AR. Patients with AR may experience changes in their everyday activities, emotions, and sleep habits, to the detriment of quality of life. Early detection and treatment can ameliorate the unpleasant effects of AR. Management includes medication, avoidance of exposure to environmental allergens and when appropriate, measures to help with associated asthma and sinusitis. Psychological interventions can also help in the management of AR.

show abstract

Drug-Induced Rhinitis: Narrative Review

Cited by 8 publications

References 31 publications

Relationship between Degrees of Nasal Obstruction and Obstructive Sleep Apnea

Relationship between Degrees of Nasal Obstruction and Obstructive Sleep Apnea

Allergic Rhinitis

Allergic rhinitis

Contact Info

Product

Resources

About