Drug Interactions

The Elderly and Drug Interactions

“…Despite many reviews, 1–5 information on drug interactions in the elderly and their possible clinical sequelae is still very incomplete. It is known, of course, that adverse drug reactions occur more often and are more severe in elderly because of altered drug distribution (loss of weight, change in lean body weight/lipid tissue), metabolism (altered liver function), and excretion (changed renal function), the latter factor being most important 3 .…”