Drug Monitoring in the Workplace: Results From the California Commercial Laboratory Drug Testing Project

Anglin, M. Douglas; Westland, Caron

doi:10.1037/e496512006-007

Cited by 3 publications

(3 citation statements)

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“…In workplace opioid testing, detection of illicit drug use is sought in a population with a generally low prevalence of opioid use [14]. In the clinical setting, the prevalence of drug exposure is much higher due to the preselection of patients for screening based upon clinical suspicion of drug exposure or prescription of the opioid drug [15].…”

Section: Urine Screening For Opioidsmentioning

confidence: 99%

Laboratory Testing for Prescription Opioids

Milone

2012

J. Med. Toxicol.

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Opioid analgesic misuse has risen significantly over the past two decades, and these drugs now represent the most commonly abused class of prescription medications. They are a major cause of poisoning deaths in the USA exceeding heroin and cocaine. Laboratory testing plays a role in the detection of opioid misuse and the evaluation of patients with opioid intoxication. Laboratories use both immunoassay and chromatographic methods (e.g., liquid chromatography with mass spectrometry detection), often in combination, to yield high detection sensitivity and drug specificity. Testing methods for opioids originated in the workplace-testing arena and focused on detection of illicit heroin use. Analysis for a wide range of opioids is now required in the context of the prescription opioid epidemic. Testing methods have also been primarily based upon urine screening; however, methods for analyzing alternative samples such as saliva, sweat, and hair are available. Application of testing to monitor prescription opioid drug therapy is an increasingly important use of drug testing, and this area of testing introduces new interpretative challenges. In particular, drug metabolism may transform one clinically available opioid into another. The sensitivity of testing methods also varies considerably across the spectrum of opioid drugs. An understanding of opioid metabolism and method sensitivity towards different opioid drugs is therefore essential to effective use of these tests. Improved testing algorithms and more research into the effective use of drug testing in the clinical setting, particularly in pain medicine and substance abuse, are needed.

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Section: Urine Screening For Opioidsmentioning

confidence: 99%

Laboratory Testing for Prescription Opioids

Milone

2012

J. Med. Toxicol.

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“…Webb summarizes Anglin and Westland's report of the proportion of positive illicit drug test results in California in 1988 to indicate that my article presents an inflated view of prevalence of alcohol and drug problems in Australia [11]. Anglin and Westland report first year findings from a drug testing project which collects data from four highvolume drug testing laboratories in California.…”

Section: Justification For Prevalence Of Alcohol and Other Drug Use Amentioning

confidence: 99%

Drug testing in the Australian workplace: Response to the commentary by G. Webb

Blaze-Temple

1993

Drug and Alcohol Review

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Gloria Webb has taken issue with a number of statements and opinions expressed in my article "Drug testing in the Australian workplace." overview of the issues", which appeared in Drug and Alcohol Review, last year. The purpose of the present paper is to respond to these comments and I shall do so in the order that they were made.Other methods of addressing alcohol and other drug problems in the workplace

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“…This is indicated by a rate of positive tests of only 1-2% for employment samples [6]. comparable published data appear to be available for Australia, results of urine testing at laboratories in the United States indicate that prevalence of illicit drug use is low in workplace populations compared with other populations tested.…”

Section: Introductionmentioning

confidence: 95%

Comments on D. Blaze‐Temple's ‘Drug testing in the Australian workplace: an overview of the issues’*

Webb¹

1993

Drug and Alcohol Review

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Drug Monitoring in the Workplace: Results From the California Commercial Laboratory Drug Testing Project

Cited by 3 publications

References 0 publications

Laboratory Testing for Prescription Opioids

Laboratory Testing for Prescription Opioids

Drug testing in the Australian workplace: Response to the commentary by G. Webb

Comments on D. Blaze‐Temple's ‘Drug testing in the Australian workplace: an overview of the issues’*

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