Drug Prescribing Pattern in Dermatophytosis at the Medical Outpatient Clinic of a Tertiary Healthcare in Karnataka, India

Giri, Vishal Prakash; Giri, Om Prakash

doi:10.5455/medscience.2015.04.8250

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…This result slightly different from the study by Giri et al which showed majority of oral prescription of terbinafine but sertaconazole was most commonly prescribed topical antifungal. 17 This was also in accordance with study by Narang et al which also showed terbinafine and topical azoles as the most common drugs used in dermatophytosis. 18 In a study conducted by Kamerkar et al it was seen that 58.28 % of drugs were prescribed as oral formulation and 41.71% were prescribed as topical formulation which was slightly different from the result obtained in our study showing 49.42% oral and 50.57% as topical prescription.…”

Section: Discussionsupporting

confidence: 90%

Drug utilization study of patients with dermatophytosis attending dermatology outpatient department in tertiary care teaching hospital in Central India

et al. 2023

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Background: Dermatophytosis is a common fungal infection in India, with prevalence ranging from 36.6% to 78.4%. Treatment options include topical and systemic antifungal agents such as amphotericin B, clotrimazole, miconazole, luliconazole, itraconazole, and terbinafine. With the availability of newer antifungal drugs, a drug utilization study is necessary to understand prescription patterns and promote rational use. Methods: This is a retrospective observational study conducted among the patients attending outpatient department of dermatology of Indira Gandhi Government Medical College and Mayo Hospital. Prescription of patients with diagnosis of tinea were collected using efficient digital database. These prescriptions were then analysed depending on their demographic profile, treatment and then results were evaluated with the help of MS Excel and results presented as percentage and proportion. Results: Total 3701 patients had tinea with 1658 females and 2043 males with majority of patients from 16 to 30 years of age. 81% medicine were prescribed using brand names with prescription containing maximum antifungal drugs followed by antihistaminic drugs. Most common drug prescribed was terbinafine (29%), followed by luliconazole (27.46%) and itraconazole (17%). Most commonly topical antifungal agents were prescribed as cream (35.80%) followed by as lotion (26.26%). Conclusions: Drug utilisation pattern study like this is very important for studying the varying prescription pattern in treatment of dermatophytosis and to make a first step towards uniform and rational drug prescription.

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Section: Discussionsupporting

confidence: 90%

Drug utilization study of patients with dermatophytosis attending dermatology outpatient department in tertiary care teaching hospital in Central India

et al. 2023

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“…Topical miconazole was the most commonly prescribed drug followed by sertaconazole and eberconazole. A similar study by Giri VP et al (2015) reported that terbinafine was the most commonly prescribed topical antifungal (22.79%), followed by sertaconazole (20.25 %) and ketoconazole (9.49 %) [15]. The use of topical azoles in our study is supported by previous studies that have reported a similar efficacy between topical allylamines and topical azoles [13].…”

Section: Discussionsupporting

confidence: 90%

Prescription Audit of Anti-fungal Treatment of Dermatophytoses in the Dermatology Out Patient Department of a Tertiary Care Hospital

2019

IJCED

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Aims: To study the prescriptions of clinically diagnosed cases of dermatophytoses, to evaluate medical treatment of clinical failure cases, any rise in serum ALT (Alanine aminotransferase) levels associated with usage of oral anti-fungal drugs, availability of drugs in the hospital pharmacy and cost minimization of different oral treatment regimens with Griseofulvin, Fluconazole, Itraconazole and Terbinafine. Settings and design: Dermatology Out Patient Department (OPD) of a tertiary care hospital, single centre prospective cohort observational study. Materials and Methods: 370 patients from the Dermatology Out Patient Department (OPD) diagnosed of dermatophytoses were enrolled. Follow-up was done 3±1 weeks apart, twice for newly diagnosed patients and once for patients on ongoing therapy. Two separate blood samples were collected 3±1 weeks apart for estimation of serum ALT. The prime lesion in each patient was graded as mild, moderate and severe. Patients were categorized as clinically cured, clinically improved, or as clinical failure following treatment. Statistical analysis used: Descriptive statistics, Fischer’s exact test and Wilcoxon’s signed rank test. Results: Azoles were the most commonly prescribed antifungals. Clinical status of patients was independent of the oral antifungal drug received (p > 0.05). A statistically significant difference in clinical status between compliant and non-compliant patients was seen (p < 0.05). A statistically significant increase in serum ALT levels was seen (p < 0.05) however, it was not clinically significant. 55.52% of drugs were unavailable in the hospital formulary. The average expenses per prescription was approximately INR 1123.55. Itraconazole was the most expensive treatment regimen followed by terbinafine and fluconazole. Conclusions: There exists a non-uniformity in the management of dermatophytoses due to lack of adequate guidance and nonavailability of drugs and clinical cure of patients depends upon compliance to therapy.

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Prospective Observational Study on Prescribing Pattern of Antifungal Drugs in the 400 Out-Patient Department of Dermatology in a Tertiary Care Hospital

Naaz

Chand

et al. 2021

Biomed. Pharmacol. J.

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Introduction: Fungal infections have been a serious disease over a few decades. Superficial fungal infections not only cause life-threatening illnesses but slowly reduce the Quality of life of patients. Objective: To study the prescribing pattern of antifungal drugs, distribution of fungal disease, and cost variability between different antifungal drugs prescribed. Materials and methods: Prospective observational study was carried out at Justice K.S. Hegde Charitable Hospital from August 2018 to April 2019. Outpatient departments patient satisfying the inclusion criteria were included in the study. Factors like age, gender, diagnosis, and type of prescribed antifungal drugs along with Price variability among different brands of the drug were considered. Antifungal drug prescriptions of patients were analyzed. Results: More than 50% of the patients were from age 21-40 yrs. Males (51.8%) were more than females (48%). The majority of the drugs prescribed were topically (64%). Tine a corpor is was the most prevalent fungal disease. The Azoles group of Antifungal was most prescribed. And the percentage variability between different brands was high. Conclusion: The study concluded the extensive use of antifungal agents. The highly prescribed drug was found to be luliconazole. The study also concluded that the use of generic prescriptions might reduce the cost of illness and enhance the rational use of the drug.

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Drug Prescribing Pattern in Dermatophytosis at the Medical Outpatient Clinic of a Tertiary Healthcare in Karnataka, India

Abstract: Aim of this study is to ascertain the drug prescribing pattern of the patients with

Cited by 3 publications

References 11 publications

Drug utilization study of patients with dermatophytosis attending dermatology outpatient department in tertiary care teaching hospital in Central India

Drug utilization study of patients with dermatophytosis attending dermatology outpatient department in tertiary care teaching hospital in Central India

Prescription Audit of Anti-fungal Treatment of Dermatophytoses in the Dermatology Out Patient Department of a Tertiary Care Hospital

Prospective Observational Study on Prescribing Pattern of Antifungal Drugs in the 400 Out-Patient Department of Dermatology in a Tertiary Care Hospital

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