Drug-related problems in diabetes and transplant patients: an observational study with home visits

Eichenberger, Patrick M.; Haschke, Manuel; Lampert, Markus L.; Hersberger, Kurt E.

doi:10.1007/s11096-011-9542-x

Cited by 15 publications

(14 citation statements)

References 29 publications

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“…On the other hand, the result of this study is lower than Ogbonna et al [28] 94% and the study in Switzerland almost all (100%) participants had at least one DTPs [29]. The discrepancies exist that would be attributed to a retrospective study method was used and participants who had took four or more drug therapy were the inclusion criteria in the above studies: those patients receiving complex drug regimen vulnerable for the existence medication related problems and would have more DTPs.…”

Section: Discussioncontrasting

confidence: 92%

“…The most frequent prescribed drug was glibenclimade with metformin (40.3%) followed by insulin injection (27.8%). Unlike this Ogbonna et al, study and Onah et al study in Nigeria, Metformin was the most commonly prescribed antidiabetics agent [28][29][30]. The discrepancy might be the utilization of metformin not optimized according to the guide line in the study setting.…”

Section: Open Access Freely Available Onlinementioning

confidence: 83%

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Drug Therapy Problems and Determinants among Ambulatory Type 2 Diabetes Mellitus Patients: Pharmacists’ Intervention in South-East Ethiopia

Argaw¹,

Hiwet²,

Derse³

2019

Endocrinol Metab Syndr

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Background: Type 2 diabetes mellitus is a major public health problem which affects the large number of people worldwide. Diabetes mellitus patients are at high risk of experiencing drug therapy problems due to different factors. Involvement of pharmacists in the management of diabetes mellitus has been shown to reduce the incidence of drug therapy problems. Objectives: To assess the prevalence of drug therapy problems, pharmacists' intervention and determinants of drug therapy problems in the management of type 2 diabetes mellitus patients. Methods: Facility based prospective cross sectional study was conducted among ambulatory type 2 diabetes mellitus patients at Madda Walabu University Goba Referral Hospital from April 1, 2017 to June 30, 2017. Data was analyzed using SPSS version 22. Descriptive statistics was performed to determine the proportion of drug therapy problems and pharmacist acceptance rate. Logistic regressions analysis was performed to identify determinants of drug therapy problems. A p-value of less than 0.05 was considered as statistically significant. Result: A total of 216 type 2 diabetes mellitus participants were included, of these 52.8% were males. The mean age of study participants was 57.07 ± 13.126 years. Among the study participants, 88% have at least one drug therapy problems. Needs additional drug therapy was the most frequent (50.2%) followed by non-compliance (21.7%). Metformin with glibenclimide and insulin were the most frequently prescribed anti diabetic drugs accounts for 40.3% and 27.8%, respectively. The recommendation done by pharmacists were 94%, the most common intervention done was to add new drug (50.2%). The acceptance rate for the interventions done was 72.6%. Conclusion: The prevalence of drug therapy problems among type 2 diabetes patients was high. Statin and metformin use not optimized. The involvement of clinical pharmacists in problems intervention should be promoted to decrease drug related risk and increase medication adherence of the diabetic patients.

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Section: Discussioncontrasting

confidence: 92%

Section: Open Access Freely Available Onlinementioning

confidence: 83%

Drug Therapy Problems and Determinants among Ambulatory Type 2 Diabetes Mellitus Patients: Pharmacists’ Intervention in South-East Ethiopia

Argaw¹,

Hiwet²,

Derse³

2019

Endocrinol Metab Syndr

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“…The classification tool has been validated and was used in many other published studies to assess DRP occurrence [10,24-26]. …”

Section: Discussionmentioning

confidence: 99%

Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia

Huri

Ling

2013

BMC Public Health

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BackgroundDrug-Related Problems (DRPs) commonly occur among type 2 diabetes mellitus (T2DM) patients. However, few studies have been performed on T2DM patients with dyslipidemia. This purpose of this study was to assess drug-related problems (DRPs) and factors associated with its occurrence.MethodsThe retrospective study involved 208 T2DM in-patients and out-patients with dyslipidemia, and was conducted at a tertiary hospital in Malaysia from January 2009 to December 2011. The identification and assessment of DRPs were based on the Pharmaceutical Care Network Europe (PCNE) tool version 5.01. The potentially inappropriate medication use in older adults was assessed based on the American Geriatrics Society updated Beers Criteria.ResultsA total of 406 DRPs were identified. Among these patients, 91.8% had at least one DRP, averaging 1.94 ± 1.10 problems per patient. The majority of T2DM patients with dyslipidemia (91.8%) had at least one DRP. The most frequent types of DRP were potential drug-drug interaction (18.0%), drug not taken or administered (14.3%) and insufficient awareness of health and diseases (11.8%). Anti-hypertensive, lipid-modifying and anti-diabetic agents were the drug classes that were most likely to be associated with DRPs. Male gender, renal impairment, polypharmacy and poor lipid control were factors that were significantly associated with DRP in diabetic dyslipidemia patients.ConclusionEarly identification of DRPs and factors associated with them are essential to prevent and resolve DRPs in T2DM patients with dyslipidemia.

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“… 43 – 65 The post-hospital discharge patient population was the most represented in these articles. 44 , 46 , 48 , 52 – 54 , 59 , 60 , 63 , 64 Other authors describe programs established in community settings 43 , 47 , 49 , 56 , 58 , 61 , 65 and clinics. 45 , 50 , 55 , 57 , 62 Other patient characteristics included being elderly, presence of a chronic disease, or number of medications.…”

Section: Introductionmentioning

confidence: 99%

“…The impact of the HV programs described in these reports were mainly related to identification of DRPs, recommendations made, or medication changes that occurred as a result of the pharmacist’s actions. 44 – 50 , 53 , 55 , 62 – 65 A variety of other impacts were also reported: satisfaction, 43 , 44 , 48 , 52 , 54 , 60 time reduction for other disciplines, 45 ADE identification, 47 , 58 perceptions of program, 51 experience, 61 adherence, 56 , 59 clinical parameters, 55 , 56 and knowledge. 48 , 56 , 60 , 61 Three programs reported economic outcomes including reduced readmission rate 52 , 59 and cost-avoidance.…”

Section: Introductionmentioning

confidence: 99%

Current perspectives on pharmacist home visits: do we keep reinventing the wheel?

Flanagan¹,

Barns²

2018

IPRP

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The scope of clinical pharmacy services available in outpatient settings, including home care, continues to expand. This review sought to identify the evidence to support pharmacist provision of clinical pharmacy services in a home care setting. Seventy-five reports were identified in the literature that provided evaluation and description of clinical pharmacy home visit services available around the world. Based on results from randomized controlled trials, pharmacist home visit interventions can improve patient medication adherence and knowledge, but have little impact on health care resource utilization. Other literature reported benefits of a pharmacist home visit service such as patient satisfaction, improved medication appropriateness, increased persistence with warfarin therapy, and increased medication discrepancy resolution. Current perspectives to consider in establishing or evaluating clinical pharmacy services offered in a home care setting include: staff competency, ideal target patient population, staff safety, use of technology, collaborative relationships with other health care providers, activities performed during a home visit, and pharmacist autonomy.

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Drug-related problems in diabetes and transplant patients: an observational study with home visits

Abstract: Visiting Tx and DM patients in their homes allowed the identification of a wide range of opportunities for pharmaceutical care as well as specific DRPs which most probably would have escaped a medication review in the pharmacy.

Cited by 15 publications

References 29 publications

Drug Therapy Problems and Determinants among Ambulatory Type 2 Diabetes Mellitus Patients: Pharmacists’ Intervention in South-East Ethiopia

Drug Therapy Problems and Determinants among Ambulatory Type 2 Diabetes Mellitus Patients: Pharmacists’ Intervention in South-East Ethiopia

Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia

Current perspectives on pharmacist home visits: do we keep reinventing the wheel?

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