Drug research and development opportunities in low- and middle-income countries: accelerating traditional medicine through systematic utilization and comprehensive synergy

Abstract

Background Though the utilization of traditional medicine has been proposed for modern drug research and development (R&D), limited research has discussed its feasible paths. In this commentary, we summarized key factors for new drug R&D under limited resources by reviewing China’s discovery of artemisinin, and raised suggestions to utilize traditional medicines in low- and middle-income countries (LMICs). Main text We suggested that systematic utilization of traditional medicine, outstanding synergy of research units at all levels and timely information-sharing mechanism should be achieved to establish a comprehensive and efficient R&D system, especially under low-resource settings. In the case of artemisinin discovery, Chinese scientists integrated documented traditional medicine experiences and modern approaches to develop drug candidates timely. Due to limited R&D resources, China adopted a collaborative way, motivating nearly all domestic research units at different levels, to develop antimalarial products. Moreover, the excellent synergy among all units through efficient information-sharing mechanisms greatly avoided work repetition and accelerated the R&D process. Conclusion Traditional medicines inspires drug discoveries in LMICs, while a comprehensive and efficient R&D system could accelerate its R&D process and save investment. The discovery of artemisinin in China gave a reliable pattern to promote sustainable development of traditional medicines and a good example to realize R&D of traditional medicine under low-resource settings.

Innovation Performance of Nursing: Competence, Motivation and Organizational Commitment as Mediating

“…The results of the development can be applied in treatment and how to deal with patients which is done in an integrated and timely manner according to patient needs. Research results (Liu et al, 2022) indicates the integration of traditional with modern. Hospitals as places of nursing care services require commitment in the organization that is integrated with the competencies of hospitals, especially nursing personnel.…”

“…For health nursing care, synergy is needed that supports patient services. The state integrates traditional medicine with modern approaches documented in the development of timely treatment methods (Liu et al, 2022). Therefore, it is necessary to increase patient participation and benefit acceptance.…”