Drug Utilization Pattern and Cost Analysis in Rheumatoid Arthritis Patients – A Cross–Sectional Study in Tertiary Care Hospital, Mumbai

Gawde, S.

doi:10.9734/bjpr/2014/2229

Cited by 5 publications

(7 citation statements)

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“…In 12 patients it was prescribed as monotherapy while the other patients were receiving it in different combinations with other DAMRDs, NSAIDs or steroids. Similar stats were revealed by a study carried out in UK by Satish et al and in India by Gawdeet al 15,10 Considering that methotrexate is the recommended first line treatment for RA, most of these prescriptions were in accordance with international guidelines.…”

Section: Discussionsupporting

confidence: 78%

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A study on prescribing patterns in patients with rheumatoid arthritis.

Naseem¹,

Zahoor

Choudhary

et al. 2021

TPMJ

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Objective: The aim of this study was to assess the prescribing patterns and frequency of use of various drug classes in patients with rheumatoid arthritis in a teaching hospital in Islamabad, Pakistan. Study Design: Descriptive Cross Sectional study. Setting: Medical Outpatient Department of HBS General Hospital, Islamabad. Period: August 2018 to March 2019. Material & Methods: Patients of rheumatoid arthritis were included in the study using non-probability consecutive sampling technique. Socio-demographic details and medication history was collected on pre-designed proforma. Data was analyzed using SPSS version 22. Results: A total of 112 patients were included in the study.108 patients (96.4%) were using disease modifying anti-rheumatic drugs. The most prescribed medication in the patients was methotrexate (n=82, 73%). One disease modifying anti-rheumatic drugs with a steroid was the preferred combination (n=32, 28%). Non-steroidal anti-inflammatory drugs (21%) and steroids (20%) were the other major drug classes among the total medications prescribed. Only one patient included in the study was using biologics. Conclusion: Conventional disease modifying anti-rheumatic drugs in combination with steroids and non-steroidal anti-inflammatory drugs are the preferred therapy in patients of Rheumatoid arthritis in local settings. Methotrexate is the most commonly used disease modifying anti-rheumatic drugs. The use of biological agents remains low as compared to the developed world owing to their high cost.

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Section: Discussionsupporting

confidence: 78%

“…The sample size was calculated from previous literature on the subject. 10 Using non-probability consecutive sampling technique, 112 patients of rheumatoid arthritis were included in the study according to the following criteria:…”

Section: Methodsmentioning

confidence: 99%

A study on prescribing patterns in patients with rheumatoid arthritis.

Naseem¹,

Zahoor

Choudhary

et al. 2021

TPMJ

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“…According to a study done in Mumbai, the cost of drugs in RA such as antisecretory agents, bisphosphonates, and calcium supplements increase the total cost of RA therapy. [19] Poly-pharmacy was also a factor seen in our study for patients taking up CAM. This is similar to the finding made by Dahiya et al who also observed that there was an increase in number of drug use in patients of RA.…”

Section: |Discussionmentioning

confidence: 64%

“…[16,18] In our study higher cost was the second most important reason for starting CAM which is in concurrence to number of previous studies. [8,12,19] Cost is an important consideration in the management of RA or other chronic ailments. According to a study done in Mumbai, the cost of drugs in RA such as antisecretory agents, bisphosphonates, and calcium supplements increase the total cost of RA therapy.…”

Section: |Discussionmentioning

confidence: 99%

Complementary and alternative medicine use in medical OPD patients of rheumatoid arthritis in a tertiary care hospital

Sadiq¹,

Kaur²,

Khajuria³

et al. 2016

Natl J Physiol Pharm Pharmacol

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Background: Complementary and alternative medicine (CAM) use is high among chronic illness like arthritis to derive additional benefits Aim and Objective: To examine CAM use among rheumatoid arthritis (RA) patients. Materials and Methods: The study was conducted in 100 patients having rheumatoid arthritis reporting to medical OPD of tertiary-care hospital. Patients were asked to respond to a predesigned questionnaire pertaining to demographic profile and CAM usage. Result: CAM use was high among RA (60%) patients more so with longer duration of disease (81.66%). Majority of patients were from rural background (80%) above 40 years age (87%) and were females. Of all, 75% patients took to CAM after antirheumatoid drugs and lack of relief was the main reason. Ayurveda was most common type of CAM (35%) used and relatives were the principal source of information (58.33%). Most of the patients (61.66%) of rheumatoid arthritis reported relief with CAM. Conclusion: CAM use is high among RA patients especially in females and patients with longer duration of disease. Lack of benefit from anti-rheumatoid drugs was the main reason of CAM usage. Ayurveda was the most common type of CAM used. Therefore, the outcome of the study calls for the attention of treating physician regarding CAM use as some orally used CAM therapies can be harmful due to possibility of interactions and heavy metals.

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“…Other studies such as Vidhya Alex et al, [2], reveals that Diclofenac gel (2.5%), Calcium and Multivitamin tablet (51.5%) is commonly prescribed. Gwade et al, [6], reports that Calcium supplements (n=69) are commonly prescribed.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Study on Pharmacoeconomic Analysis of Rheumatoid Arthritis Patient in Two Different Hospitals in Tamil Nadu

Prakasam¹,

Krishna²,

Aleena³

et al. 2020

Int J Pharm Pharm Sci

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Objective: The objective of the present study is to compare the prescribing patterns and cost of illness of Rheumatoid arthritis patients in two different hospitals. Methods: This is an observational study conducted in two different tertiary care hospitals in Salem district after obtaining approval of the Institutional Ethics Committee (IEC) (Registration Number EC/PHARM D/2019.06). A sample size of 102 (above 18 y) patients were included (52 from group 1 hospital and 50 from group 2 hospital). The study was conducted over a period of 6 mo from February 2019 to July 2019. The cost was collected by a patient face-to-face interview. Results: Out of 102 patients, females (57.84%) patients were more prevalent than men with the age group of 50-59 y in both groups. Methotrexate was most commonly prescribed drug in group 1(36.5%), whereas in group 2 are Sulfasalazine (37%). Among the DMARDs unit cost of methotrexate is high but the monthly cost was high for Sulfasalazine, because the methotrexate is prescribed on a once-weekly basis while sulfasalazine is taken twice a day. The cost of NSAIDs comes around 46.47% of the total drug cost of the month. In steroids, cost comes around 11.73% of the total drug cost. Among the direct cost of two groups, the drug cost and transportation cost is higher when compared with other costs. Indirect costs such as lost wages, due to disease is higher in group 1. Conclusion: The study concluded that the burden of RA to the patient is huge, Appropriate standard prescribing guidelines should be developed and implementation of the rational drug must be promoted. Polypharmacy was reported in group 1 hospital, the progression of symptoms was the same in both hospitals, it increases the cost of therapy and overall cost of patients. Hence it becomes vital to diagnose and control the disease at an early stage to control the economic burden on the patient.

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Drug Utilization Pattern and Cost Analysis in Rheumatoid Arthritis Patients – A Cross–Sectional Study in Tertiary Care Hospital, Mumbai

Cited by 5 publications

References 0 publications

A study on prescribing patterns in patients with rheumatoid arthritis.

A study on prescribing patterns in patients with rheumatoid arthritis.

Complementary and alternative medicine use in medical OPD patients of rheumatoid arthritis in a tertiary care hospital

A Comparative Study on Pharmacoeconomic Analysis of Rheumatoid Arthritis Patient in Two Different Hospitals in Tamil Nadu

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