Drug utilization study in a neonatology unit of a tertiary care hospital in eastern India

Chatterjee, Suparna; Mandal, Ananya; Lyle, Nazmun; Mukherjee, Suchandra; Singh, Amit Kumar

doi:10.1002/pds.1469

Cited by 41 publications

(62 citation statements)

References 6 publications

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“…This finding was similar to the two studies conducted in eastern and southern India in 2007 and 2011 [12][13][14]. Another study by Smythe et al documented equal number of male and female individuals admitted to the ICU; however, with a significantly higher average age of 65 years [15].…”

Section: Al-zakwani Et Alsupporting

confidence: 88%

Drug Utilization Pattern in an Intensive Care Unit at a Tertiary Care Teaching Hospital in Oman

Al‐Zakwani

Al-thuhli

Al-Hashim

et al. 2017

Asian J Pharm Clin Res

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Objectives: The objective of this study was to evaluate the drug prescribing trends in the intensive care unit (ICU) and correlate them with the disease patterns and patients' outcomes. Methods:The case records of patients admitted to the ICU at Sultan Qaboos University Hospital, a teaching hospital in Oman, during a 5-month period between June 1 st and October 31 st 2013 were analyzed. The variables collected included demographic and clinical characteristics as well as duration of hospitalization, indications, and utilization of different drugs.Results: A total of 138 patients were evaluated with an average age of 46±19 years. The average length of stay at ICU was 4.5±3.5 days. The average number of drugs per prescription was 8.0±4.6. The most common route used was the parenteral route (66%) followed by the enteral route (25%).

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Section: Al-zakwani Et Alsupporting

confidence: 88%

Drug Utilization Pattern in an Intensive Care Unit at a Tertiary Care Teaching Hospital in Oman

Al‐Zakwani

Al-thuhli

Al-Hashim

et al. 2017

Asian J Pharm Clin Res

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“…A study reported average number of drugs per encounter as 4.8 which is quiet comparable with our study. 25 Another study reported mean drug usage as 3.6 drugs per infant. 3 However, other studies reported mean drug usage as 7 and 11.1 drugs per neonate respectively.…”

Section: Duration Of Hospital Stay (In Days)mentioning

confidence: 99%

Drug utilization study in neonatal intensive care unit of a tertiary care teaching hospital

Vaghela¹,

Sukhlecha

2017

Int J Basic Clin Pharmacol

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Neonates are a very vulnerable group to adverse drug reactions due to immaturity of their body functions. So, great care needs to be taken to prescribe drugs to them. Recent advances in prenatal care have resulted in an increase in drug exposure rates in pregnant mothers, causing infants to be exposed to aptitude of different drugs, even when in utero. Advances in medical technology have also resulted in improved survival rates in both term and preterm infants, including high risk and low birth weight infants. Because of these changes in the medical ABSTRACT Background: Sick and pre-term neonates are admitted in neonatal intensive care units (NICU) and treated. A great care needs to be taken to use drugs in neonates due to the immaturity of their body functions. There is a lack of standard drug prescribing guideline in children, especially neonates because; safety and efficacy for a majority of drugs have not been established in them. The objectives of the study were to evaluate the drug utilization pattern in NICU of a teaching hospital and to identify problems in drug utilization and suggest measures, if needed. Methods: A prospective, observational study was carried out in NICU for duration of one year. Demographic details like age, sex, birth weight, duration of hospitalization was recorded from the case files of neonates. The morbid condition, treatment with drugs and other supportive modalities were recorded. The outcome of treatment was also noted. WHO drug utilization core indicators were also evaluated. Results: Out of 623 admissions in NICU, 56% were males. There were 56% of neonates who were born pre-term. The maximum used drugs were Vitamin K (73%) and antibiotics (64%). The antibiotics were mainly from penicillin and aminoglycoside groups. Respiratory distress syndrome (19%) and neonatal sepsis (16%) were the most common causes for admission. Out of total admissions, 64% were discharged following recovery, while, 12% had expired. Conclusions: Drugs usage in neonates should be minimal and should be prescribed from essential drug list. Antibiotic policy needs to be formulated for hospitals to minimize antibiotic usage and prevent development of resistance.

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“…Such issues therefore call for a close monitoring of drug prescribing trends in neonates and infants. 5 While prescribing for children's a number of knowledgebased skills and practical considerations are required. 6 Medical personnel providing health care for neonates in developing countries are facing a number of challenges during their day-to-day practice of medicine due to inadequate infrastructure, irregular supply of drugs and other health care facilities.…”

Section: Introductionmentioning

confidence: 99%

“…Although the role of antimicrobial agents is vital, its irrational use often leads to emergence and dissemination of drug resistance strains. 5 Drug utilization was defined by the world health organization (WHO) in 1997 as the marketing, distribution, prescription and use of drugs in our society, with special emphasis on the resulting medical, social and economic consequences.…”

Section: Introductionmentioning

confidence: 99%

Study of drug utilization in intensive care management of neonates at tertiary care hospital

Neeta

Singh

2017

Int J Basic Clin Pharmacol

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Background: Newborn infants form a highly vulnerable group. Compared to adults they are more prone to adverse drug events. Exposure to multiple drugs is also known to be a leading factor in their well-being. Many advances have been made in this area, yet there is a paucity of information to guide rational prescribing in newborns. This study was conducted to evaluate the drug prescribing trends in a Neonatal Intensive Care Unit (NICU) of a tertiary care hospital in Bidar.Methods: A prospective study was undertaken, over a period of 3 months at the government teaching hospital, Bidar. Neonates of either sex admitted to NICU were included. Data collection was done by scrutinizing the inpatient case sheets and investigation reports.Results: A total of 100 neonates were admitted and 11 deaths were noted. Most common cause for admission was septicaemia. The total number of drugs prescribed was 488. The average number of drugs per prescription was 4.9. Antimicrobials were the commonest agents prescribed and intravenous route was the commonest route of drug administration. Most of the drugs were prescribed by generic names.Conclusions: In our study it was observed that polypharmacy is commonly observed practice in NICU patients. Most of the antibiotics were prescribed empirically. The dose and frequency of administration was mostly as per the standard guidelines.

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Drug utilization study in a neonatology unit of a tertiary care hospital in eastern India

Cited by 41 publications

References 6 publications

Drug Utilization Pattern in an Intensive Care Unit at a Tertiary Care Teaching Hospital in Oman

Drug Utilization Pattern in an Intensive Care Unit at a Tertiary Care Teaching Hospital in Oman

Drug utilization study in neonatal intensive care unit of a tertiary care teaching hospital

Study of drug utilization in intensive care management of neonates at tertiary care hospital

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