Dry response and acclimated characteristics of people ascending the Tibetan Plateau

Wang, Dengjia; Sun, Xin; Song, Cong; Wang, Yingying; Duan, Guannan; Hu, Jiale

doi:10.1016/j.jtherbio.2023.103493

Cited by 3 publications

(1 citation statement)

References 40 publications

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“…Dry air, especially in arid climates or heated indoor environments, can cause the nasal mucosa to become dry and prone to bleeding. 7 Irritants like pollutants, chemical fumes, or excessive use of nasal sprays can also irritate the nasal lining and trigger nosebleeds. 8 Infections such as sinusitis or upper respiratory tract infections can lead to inflammation and congestion of the nasal mucosa.…”

Section: Introductionmentioning

confidence: 99%

Evaluation and management of acute epistaxis in the emergency department

Abduljabbar,

Abdulmahdi,

Alalshojaa

et al. 2023

Int J Community Med Public Health

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Acute epistaxis, or nosebleed, is a common presentation in the emergency department (ED) that requires a systematic evaluation and prompt management. The assessment involves considering the severity of bleeding, identifying underlying causes, and implementing appropriate interventions. Modifiable risk factors, such as medication review, nasal hygiene, avoidance of nasal trauma, and humidification, should be addressed to prevent recurrence. Referral to specialists is necessary for cases of recurrent or severe bleeding, suspected underlying causes, or inadequate response to initial management. Collaboration between ED healthcare providers and specialists ensures comprehensive evaluation, specialized interventions, and long-term management. Regular follow-up appointments and patient education are essential for monitoring progress, adjusting treatment, and preventing complications. By employing a comprehensive approach, healthcare providers aim to alleviate distress, achieve hemostasis, identify underlying etiologies, and optimize patient outcomes in the ED.

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Section: Introductionmentioning

confidence: 99%

Evaluation and management of acute epistaxis in the emergency department

Abduljabbar,

Abdulmahdi,

Alalshojaa

et al. 2023

Int J Community Med Public Health

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A simplified model for correcting the heating capacity of air source heat pumps in high-altitude plateau areas

Lyu,

Wang,

et al. 2024

Energy

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Evaluation of pulmonary artery pressure, blood indices, and myocardial microcirculation in rats returning from high altitude to moderate altitude

Yan,

Ma,

Tian

et al. 2024

Eur Radiol Exp

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Background To investigate changes in pulmonary artery pressure (PAP), blood indices, and myocardial microcirculation in rats returning from high altitude (HA) to moderate altitude (MA). Methods Forty 4-week-old male Sprague-Dawley rats were randomly divided into four groups with ten rats in each group. One group was transported to the MA area (MA-group), and the other three groups were transported to HA (HA-group-A, HA-group-B, and HA-group-C). After 28 weeks of age, the rats from the HA area were transported to the MA area for 0 days, 10 days, and 20 days, respectively. PAP, routine blood tests, and computed tomography myocardial perfusion indices were measured. Results Compared with the MA-group, the body weight of HA-groups decreased (p < 0.05), and PAP in HA-group-A and HA-group-B increased (p < 0.05). In the HA groups, PAP initially increased and then decreased. Compared with the MA-group, red blood cells (RBC), hemoglobin (HGB), and hematocrit (HCT) of rats in HA-group-A increased (p < 0.05). Compared with the HA-group-A, RBC, HGB, and HCT of HA-group-B gradually decreased (p < 0.05) while MCV decreased (p < 0.05), and PLT of HA-group-C increased (p < 0.05). Compared with the MA group, blood flow (BF) and blood volume (BV) of the HA-group-A decreased (p < 0.05). Compared with the HA-group-A, TTP increased first and then decreased (p < 0.05), and BF and BV increased gradually (p < 0.05). Pathological results showed that myocardial fiber arrangement was disordered, and cell space widened in the HA group. Conclusion PAP, blood parameters, and myocardial microcirculation in rats returning from high to MA exhibited significant changes. Relevance statement This study provides an experimental basis for understanding the physiological and pathological mechanisms during the process of deacclimatization to HA and offers new insights for the prevention and treatment of deacclimatization to HA syndrome. Key Points Forty rats were raised in a real plateau environment. Myocardial microcirculation was detected by CT myocardial perfusion imaging. The PAP of the unacclimated rats increased first and then decreased. The myocardial microcirculation of the deacclimated rats showed hyperperfusion changes. Graphical Abstract

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Dry response and acclimated characteristics of people ascending the Tibetan Plateau

Cited by 3 publications

References 40 publications

Evaluation and management of acute epistaxis in the emergency department

Evaluation and management of acute epistaxis in the emergency department

A simplified model for correcting the heating capacity of air source heat pumps in high-altitude plateau areas

Evaluation of pulmonary artery pressure, blood indices, and myocardial microcirculation in rats returning from high altitude to moderate altitude

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