2022
DOI: 10.1016/j.mtbio.2022.100494
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Dual-catalytic CuTPP/TiO2 nanoparticles for surface catalysis engineering of cardiovascular materials

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Cited by 3 publications
(3 citation statements)
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“…Several surface treatments have been proposed to improve the surface properties of titanium-based alloys to prevent thrombus formation [20] . Among them, a promising approach is the development of multifunctional surfaces that mimic the endothelial environment [ 20 , [77] , [78] , [79] ] or that direct the cardiovascular cells fate [80] , acting not only in the prevention of thrombus formation, but also in the stimulation of endothelialization.…”
Section: Discussionmentioning
confidence: 99%
“…Several surface treatments have been proposed to improve the surface properties of titanium-based alloys to prevent thrombus formation [20] . Among them, a promising approach is the development of multifunctional surfaces that mimic the endothelial environment [ 20 , [77] , [78] , [79] ] or that direct the cardiovascular cells fate [80] , acting not only in the prevention of thrombus formation, but also in the stimulation of endothelialization.…”
Section: Discussionmentioning
confidence: 99%
“…Copper tetraphenyl porphyrin (CuTPP) is a biomolecule that possesses catalytic functions of multiple enzymes, such as eNOS and SOD/CAT (Figure 12). Luying Liu et al have hypothesized that Cu chelated ion in the porphyrin ring of CuTPP could viably produce NO in vivo by catalyzing the endogenous NO donor nitroso-glutathione (GSNO) [74]. By exploiting the electron transfer capabilities of copper tetraphenyl porphyrin/titanium dioxide nanoparticles (CuTPP/TiO 2 -NPs), a dual catalytic surface with both nitric oxide (NO) production and reactive oxygen species (ROS) removal activities was established.…”
Section: Copper Tetraphenyl Porphyrin/titanium Dioxide Nanoparticlesmentioning
confidence: 99%
“…It exhibited antithrombotic and anti-inflammatory properties, modulation of vascular wall cells (endothelial cells and smooth muscle cells). The novel dual catalytic and endothelial bionic strategy presents a promising solution with which to address the clinical challenges associated with blood contact devices [74].…”
Section: Copper Tetraphenyl Porphyrin/titanium Dioxide Nanoparticlesmentioning
confidence: 99%