Dual-effects of caffeinated hyalurosomes as a nano-cosmeceutical gel counteracting UV-induced skin ageing

Elsheikh, Manal A; Gaafar, Passent M. E.; Khattab, M.; Abouhelwah, Mohamed K.; Noureldin, Mohamed H.; Abbas, Haidy

doi:10.1016/j.ijpx.2023.100170

Cited by 3 publications

(2 citation statements)

References 67 publications

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“…Skin aging is a multifaceted phenomenon encompassing both endogenous and exogenous processes [13]. Among the external factors, ultraviolet (UV) radiation stands out as the primary contributor to skin photoaging [14].…”

Section: Introductionmentioning

confidence: 99%

Marine Bioactive Peptides: Anti-Photoaging Mechanisms and Potential Skin Protective Effects

Zhang,

Zhuang,

et al. 2024

CIMB

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Skin photoaging, resulting from prolonged exposure to ultraviolet radiation, is a form of exogenous aging that not only impacts the aesthetic aspect of the skin but also exhibits a strong correlation with the onset of skin cancer. Nonetheless, the safety profile of non-natural anti-photoaging medications and the underlying physiological alterations during the process of photoaging remain inadequately elucidated. Consequently, there exists a pressing necessity to devise more secure interventions involving anti-photoaging drugs. Multiple studies have demonstrated the noteworthy significance of marine biomolecules in addressing safety concerns related to anti-photoaging and safeguarding the skin. Notably, bioactive peptides have gained considerable attention in anti-photoaging research due to their capacity to mitigate the physiological alterations associated with photoaging, including oxidative stress; inflammatory response; the abnormal expression of matrix metalloproteinase, hyaluronidase, and elastase; and excessive melanin synthesis. This review provides a systematic description of the research progress on the anti-photoaging and skin protection mechanism of marine bioactive peptides. The focus is on the utilization of marine bioactive peptides as anti-photoaging agents, aiming to offer theoretical references for the development of novel anti-photoaging drugs and methodologies. Additionally, the future prospects of anti-aging drugs are discussed, providing an initial reference for further research in this field.

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Section: Introductionmentioning

confidence: 99%

Marine Bioactive Peptides: Anti-Photoaging Mechanisms and Potential Skin Protective Effects

Zhang,

Zhuang,

et al. 2024

CIMB

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“…Additionally, UV light causes the skin to have acute inflammatory reactions that speed up the aging process . Previously, it was known that topical application of antioxidants protects skin from oxidative damage . Several natural antioxidant ingredients also have anti-inflammatory properties that can be used in the treatment of oxidative damage-associated conditions such as photoaging .…”

Section: Introductionmentioning

confidence: 99%

Taif Rose Oil Ameliorates UVB-Induced Oxidative Damage and Skin Photoaging in Rats via Modulation of MAPK and MMP Signaling Pathways

Abdallah,

Koshak,

Farag

et al. 2023

ACS Omega

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Short-wave UVB (ultraviolet B) causes rapid oxidative damage to the skin. Rose water is obtained mainly from the petals of Rosa damascena Mill. (Rosaceae) and used traditionally to hydrate dry skin and reduce signs of aging. This work aimed at evaluating the possible protective potential of the prepared eco-friendly Taif rose oil nanoemulsion (ROSE-NANO) against UVB-induced photoaging in adult male Wistar rats. Taif rose oil (ROSE) was obtained from R. damascene by classical steam distillation and formulated in emulgel (100 mg/g). In addition, the oil was formulated in ROSE-NANO-loaded emulgel (50 and 100 mg/g) to enhance the effect of ROSE. All prepared formulas were tested topically for their potential protective effect in UV-induced skin photoaging. The obtained results demonstrated that application of ROSE-NANO-loaded emulgel resulted in superior antiaging potency over ROSE emulgel based on histological studies as well as biochemical evaluations via amendment in CAT and SOD activities, decreasing the concentration of the inflammatory markers and preventing collagen fragmentation through reduction of MMP-9 content in fibroblasts. Moreover, a significant decrease in mRNA expression of NF-KB, JNK, ERK1/2, and p38 MAPK genes was observed. In conclusion, the current study provides scientific evidence for the traditional use of rose oil in skin aging. Moreover, the NANO formula showed promising efficacy as a skin photoprotector against UV-induced oxidative damage and skin aging.

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Combined photodynamic therapy and hollow microneedle approach for effective non-invasive delivery of hypericin for the management of imiquimod-induced psoriasis

Zewail,

Abbas,

El Sayed

et al. 2024

Journal of Drug Targeting

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Dual-effects of caffeinated hyalurosomes as a nano-cosmeceutical gel counteracting UV-induced skin ageing

Cited by 3 publications

References 67 publications

Marine Bioactive Peptides: Anti-Photoaging Mechanisms and Potential Skin Protective Effects

Marine Bioactive Peptides: Anti-Photoaging Mechanisms and Potential Skin Protective Effects

Taif Rose Oil Ameliorates UVB-Induced Oxidative Damage and Skin Photoaging in Rats via Modulation of MAPK and MMP Signaling Pathways

Combined photodynamic therapy and hollow microneedle approach for effective non-invasive delivery of hypericin for the management of imiquimod-induced psoriasis

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