Dual-Energy CT-Based Iodine Quantification in Liver Tumors – Impact of Scan-, Patient-, and Position-Related Factors

Schmidt, Cynthia; Baeßler, Bettina; Nakhostin, Dominik; Das, Arijit; Eberhard, Matthias; Alkadhi, Hatem; Euler, André

doi:10.1016/j.acra.2020.04.021

Cited by 6 publications

(2 citation statements)

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“…Improved contrast of iodine maps makes enhancing lesions or vessels more conspicuous and allows better delineation of bowel ischemia and lung hypoperfusion [ 6 , 47 ].…”

Section: Resultsmentioning

confidence: 99%

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Pros and Cons of Dual-Energy CT Systems: “One Does Not Fit All”

2023

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Dual-energy computed tomography (DECT) uses different energy spectrum X-ray beams for differentiating materials with similar attenuation at a certain energy. Compared with single-energy CT, it provides images with better diagnostic performance and a potential reduction of contrast agent and radiation doses. There are different commercially available DECT technologies, with machines that may display two X-ray sources and two detectors, a single source capable of fast switching between two energy levels, a specialized detector capable of acquiring high- and low-energy data sets, and a filter splitting the beam into high- and low-energy beams at the output. Sequential acquisition at different tube voltages is an alternative approach. This narrative review describes the DECT technique using a Q&A format and visual representations. Physical concepts, parameters influencing image quality, postprocessing methods, applicability in daily routine workflow, and radiation considerations are discussed. Differences between scanners are described, regarding design, image quality variabilities, and their advantages and limitations. Additionally, current clinical applications are listed, and future perspectives for spectral CT imaging are addressed. Acknowledging the strengths and weaknesses of different DECT scanners is important, as these could be adapted to each patient, clinical scenario, and financial capability. This technology is undoubtedly valuable and will certainly keep improving.

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“…Improved contrast of iodine maps makes enhancing lesions or vessels more conspicuous and allows better delineation of bowel ischemia and lung hypoperfusion [ 6 , 47 ].…”

Section: Resultsmentioning

confidence: 99%

“…Studies comparing iodine sensitivity among DECT scanners concluded that it correlates mainly with better spectral performance and is also influenced by other factors such as image reconstruction techniques, patient size, and lesion location [ 34 , 47 , 48 , 49 , 50 ].…”

Section: Resultsmentioning

confidence: 99%