Dual Energy X-ray Absorptiometry Scanning and Bone Health: The Pressing Need to Raise Awareness Amongst Pakistani Women

Anwar, Farah; Iftekhar, Hiba; Taher, Tasneem; Kazmi, Syeda Kanza; Rehman, Fatima Z; Humayun, Minhal; Mahmood, Samar

doi:10.7759/cureus.5724

Cited by 4 publications

(4 citation statements)

References 20 publications

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“…Osteoporosis is known to have various negative impacts on patients, affecting their physical, mental, and emotional well-being [ 24 ]. Fragility fractures associated with osteoporosis are linked to increased rates of morbidity and mortality [ 25 ]. Following a fragility fracture, it is possible to experience complications such as fracture-related persistent discomfort and limitations on daily activities [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

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Dual Energy X-ray Absorptiometry Scanning for Osteoporosis Detection: Analysis of Patients at a Tertiary Care Hospital

Nisar,

Hamza,

Awan

et al. 2023

Cureus

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Introduction: Dual-energy X-ray absorptiometry (DEXA) scanning is a rapid and accurate noninvasive procedure utilized to measure bone mineral density (BMD) and diagnose osteoporosis. The primary objective of this study was to assess the prevalence of osteoporosis in different regions of the body using DEXA scanning in patients attending a tertiary care private hospital. Additionally, we aimed to raise awareness about approved diagnostic methods for osteoporosis. Methodology: For this retrospective study, a sample size of 384 participants was determined. The selection of participants was based on convenience sampling, considering their availability and accessibility. Data were collected from adult patients aged 18 years and above who underwent DEXA scanning. The information was compiled using Microsoft Excel, obtained from the patient's treating physicians, and evaluated by two medical graduates. Statistical analyses were performed using IBM SPSS Statistics version 26.0 (IBM Corp., Armonk, NY). Results: The findings unveiled an overarching osteoporosis prevalence of 38.5%, accompanied by distinctive figures of 38.7%, 8.9%, and 38.4% in the lumbar, hip, and forearm regions, respectively. Furthermore, the occurrence of osteopenia was found in 33% of participants in the lumbar region, 35.1% in the hip region, and 39.7% in the forearm region. Additionally, no significant association was found between gender and overall osteoporosis prevalence, suggesting that the susceptibility to osteoporosis did not significantly differ between genders. Moreover, the study emphasized the variations in bone density across different skeletal regions, with the forearm region displaying the lowest mean T-score and Z-score. Conclusions: The results of this study on osteoporosis prevalence in the lumbar, hip, and forearm regions indicate varying rates among these skeletal sites. Notably, both male and female patients demonstrated an equal susceptibility to developing osteoporosis. Interestingly, the forearm region emerged as the most common site for osteoporosis in males (34.6%), while the lumbar region was the most common in females (41.6%).

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Section: Discussionmentioning

confidence: 99%

“…Fragility fractures associated with osteoporosis are linked to increased rates of morbidity and mortality [25]. Following a fragility fracture, it is possible to experience complications such as fracture-related persistent discomfort and limitations on daily activities [25].…”

Section: Yearmentioning

confidence: 99%

Dual Energy X-ray Absorptiometry Scanning for Osteoporosis Detection: Analysis of Patients at a Tertiary Care Hospital

Nisar,

Hamza,

Awan

et al. 2023

Cureus

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“…DEXA is a low dose X-Ray scan to measure bone density to access and diagnose condition of osteoporosis. DEXA scan is also recognised by WHO as a gold standard to measure the BMD with most examined sites as hip and lower back area (22). VAS is a method to measure chronic and acute pain.…”

Section: Assessmentmentioning

confidence: 99%

Effect of Integrated Ayurveda and Yoga Therapy (IAYT) on osteoporosis detected in breast cancer patient on remission- A single case study

Tripathi¹,

Panchal²,

Aliyas³

2020

IMCR

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This is a case study for invasive ductal carcinoma diagnosed in a patient aged 60 years in 2015. She went through chemotherapy and radiotherapy and was on remission in 2016. Bone density degeneration was the side effect from the breast cancer treatment. After trying the conventional treatment, she was not satisfied, she came to Union Yoga Ayurveda (UYA), Singapore. She came to clinic looking for alternative therapy to help her increase her bone density, cope up with weakness and overall mental and physical wellbeing. The patient was given holistic treatment of yoga and Ayurveda, involving patra pinda sweda (herbal compress) and picchu (herbal soaked gauze pieces). The yoga therapy involved asanas practise to increase strength, breathing and meditation for overall wellbeing. The patient was not on any other treatment/medication during the entire treatment. After uninterrupted therapy for six months there was an increase in her bone density along with increase in energy level. The patient case study is an attempt to provide yoga and Ayurveda as an alternative/supportive treatment for remission management osteoporosis from breast cancer patients.

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“…Dual energy X-ray absorptiometry (DXA) scan for identification of bone mineral density is the gold standard to diagnose osteoporosis. The DXA scan is a costly method to assess BMD for diagnosis of osteoporosis in poor, low- and middle-income peoples [ 3 ]. And it is only detected with BMD in the specific region of bone tissue not in the whole-body bones.…”

Section: Introductionmentioning

confidence: 99%

Serum sclerostin levels as a diagnostic marker for osteoporosis

Paranthaman

2024

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Osteoporosis is asymptomatic, in which low bone-mass and micro-architectural deterioration of bone tissue leads to increasing bone fragility and fracture. Vertebral and hip fractures lead to increased mortality, resulting in enormous health care costs. BMD testing by DEXA is used in diagnosis of osteoporosis. However, low-and middle-income populations are unable to conduct periodic examinations of bone mineral status. Thus, current study is mainly aimed at finding a cost-effective diagnostic-marker for osteoporosis. 170 participants, of whom 51 had osteoporosis, 62 had osteopenia and 57 had normal bone-mass. Selection of individuals was based on DEXA scan BMD. Sclerostin was determined by ELISA. The variables were compared using ANOVA test and ROC analysis was performed. Sclerostin levels were significantly decreased in osteoporosis (4.62 ą 1.6 ng/mL) and osteopenia (4.92 ą 1.4 ng/mL) compared with controls (5.74 ą 1.3 ng/mL), (p < 0.0001). Sclerostin level 5.6 ng/mL is the cut-off value for diagnostic purpose, according to good sensitivity and specificity. In patients with osteopenia and osteoporosis, decreased sclerostin levels were associated with an increased disease risk. These relationships were independent of BMD and bone turnover, suggesting that Sclerostin levels may reflect disease-severity in osteoporosis. Sclerostin measurements could become a useful clinical index for diagnosis of osteoporosis.

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Dual Energy X-ray Absorptiometry Scanning and Bone Health: The Pressing Need to Raise Awareness Amongst Pakistani Women

Cited by 4 publications

References 20 publications

Dual Energy X-ray Absorptiometry Scanning for Osteoporosis Detection: Analysis of Patients at a Tertiary Care Hospital

Dual Energy X-ray Absorptiometry Scanning for Osteoporosis Detection: Analysis of Patients at a Tertiary Care Hospital

Effect of Integrated Ayurveda and Yoga Therapy (IAYT) on osteoporosis detected in breast cancer patient on remission- A single case study

Serum sclerostin levels as a diagnostic marker for osteoporosis

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