2024
DOI: 10.3389/fncel.2023.1298685
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Dual isolation of primary neurons and oligodendrocytes from guinea pig frontal cortex

Roisin A. Moloney,
Carlton L. Pavy,
Richard G. S. Kahl
et al.

Abstract: Primary cell culture is a technique that is widely used in neuroscience research to investigate mechanisms that underlie pathologies at a cellular level. Typically, mouse or rat tissue is used for this process; however, altricial rodent species have markedly different neurodevelopmental trajectories comparatively to humans. The use of guinea pig brain tissue presents a novel aspect to this routinely used cell culture method whilst also allowing for dual isolation of two major cell types from a physiologically … Show more

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