2022
DOI: 10.1039/d2an01220k
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Dual-mode ion-selective electrodes and distance-based microfluidic device for detection of multiple urinary electrolytes

Abstract: Here, we developed a microfluidic paper device by combining ion-selective electrodes (ISE) and a distance-based paper device (dPAD) for simultaneous potentiometric and colorimetric detection of urine electrolytes including K+, Na+...

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Cited by 8 publications
(3 citation statements)
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“…Reference electrode membrane was prepared by mixing 200 mg poly(butyl methacrylate-co-methyl methacrylate) (P(BMA-co-MM)), 68 mg KCl, and 5 mg tetradodecylammonium tetrakis(4-chlorophenyl) borate (ETH500) in 1 mL THF. [47][48][49] Then, 6 μL (2 μL × 3) of reference membrane was drop-cast on reference electrode zone. The stencil-printed ISEs were placed in a desiccator to allow THF evaporation for overnight.…”
Section: Methodsmentioning
confidence: 99%
“…Reference electrode membrane was prepared by mixing 200 mg poly(butyl methacrylate-co-methyl methacrylate) (P(BMA-co-MM)), 68 mg KCl, and 5 mg tetradodecylammonium tetrakis(4-chlorophenyl) borate (ETH500) in 1 mL THF. [47][48][49] Then, 6 μL (2 μL × 3) of reference membrane was drop-cast on reference electrode zone. The stencil-printed ISEs were placed in a desiccator to allow THF evaporation for overnight.…”
Section: Methodsmentioning
confidence: 99%
“…The balance of sodium and potassium in the body is important for the regulation of blood pressure and fluid balance. 223 Typically, the kidneys regulate the amount of sodium and potassium excreted in urine to maintain a healthy balance in the body. However, certain medical conditions or medications can cause imbalances in sodium and potassium levels in urine, which can be determined through urine analysis.…”
Section: Biofluidsmentioning
confidence: 99%
“…Paper substrates share common advantages, such as a good biocompatibility with biomolecules (e.g., proteins and nucleic acids) and pump-free fluid transport through the capillarity [6,7]. The paper-based devices are compatible with various quantitative detection mechanisms, such as colorimetry [8,9], electrochemistry [10][11][12], chemiluminescence [13], and electrical conductivity [14]. Among them, the colorimetric enzyme-linked immunosorbent assay (ELISA) on a paper-based device, is of great potential.…”
Section: Table Of Contentsmentioning
confidence: 99%