“…Resonantly enhanced light transmission, leading to extraordinary optical transmission (EOT) phenomena, is a fascinating property exhibited by periodic arrays of sub-wavelength holes, periodically milled in an optically thick (>100 nm) metal lm. 1,2 Since the seminal report on EOT, 1 metal nanohole (NH) distributions have attracted worldwide interest for several applications: for instance, plasmonic solar cells and photodetectors, 3 plasmonic color-lter devices, 4,5 surface enhanced Raman scattering, 6 surface enhanced uorescence spectroscopy, 7,8 monitoring of surface-binding events in chemical and biochemical sensing, [9][10][11] preferably by microuidic-chip based detection due to the benets of a simple optical set-up, dense integration of sensors, multiplexing for parallel and selective analyte sampling in miniaturized and high throughput sensors. 12,13 From the fundamental standpoint, resonant transmission phenomena were rst ascribed to coupling between free-space photons and Bloch-wave surface plasmon polaritons mediated by diffractive hole grating (grating-coupling model).…”