Dual-potential electrochemiluminescence of single luminophore for detection of biomarker based on black phosphorus quantum dots as co-reactant

Zinc–Metal Organic Frameworks: A Coreactant-free Electrochemiluminescence Luminophore for Ratiometric Detection of miRNA-133a

“…16 Dong's team developed a ratiometric ECL biosensor by utilizing RuNDs as a single luminophore in the presence of BPQDs as the anodic coreactant and K 2 S 2 O 8 as the cathodic coreactant for the detection of tumor marker mucin 1. 17 However, in order to obtain an excellent ECL signal, at least one suitable coreactant needs to be added in the abovementioned ratiometric strategies. The addition of the coreactant would affect the detection environment, resulting in poor stability of the ECL system and causing measurement errors.…”

“…Wang’s group proposed another ratiometric ECL biosensor based on luminol as a single emitter and H 2 O 2 as an effective coreactant to realize the sensitive detection of carcinoembryonic antigens . Dong’s team developed a ratiometric ECL biosensor by utilizing RuNDs as a single luminophore in the presence of BPQDs as the anodic coreactant and K 2 S 2 O 8 as the cathodic coreactant for the detection of tumor marker mucin 1 . However, in order to obtain an excellent ECL signal, at least one suitable coreactant needs to be added in the abovementioned ratiometric strategies.…”

Tetrakis (4-carboxyphenyl) porphyrin and Ru(bpy)32+ modified SiO2 nanospheres for potential and wavelength resolved electrochemiluminescence

“…20 The intensity of ECL-2 gradually decreased with the increase of the K 2 S 2 O 8 concentration, which might be due to the reaction of S 2 O 8 2À and Ru(bpy) 3 2+ , leading to a decrease in the amount of Ru(bpy) 3 2+ participating in ECL-2. 30 In Fig. S7B (ESI †), the intensity of ECL-2 significantly enhanced with the increase of the concentration of TPrA, due to TPrA as a coreactant significantly increasing the ECL efficiency of Ru(bpy) 3 2+ .…”

Ratiometric Electrochemiluminescence of Zirconium Metal–Organic Framework as a Single Luminophore for Sensitive Detection of HPV-16 DNA

“…The biosensor based on the single luminophore with dual emissions has aroused widespread interest and attention owing to the fact that the two synchronized signals significantly improve accuracy and authenticity compared to the two independent signals. For example, Chu’s team developed RuNDs to detect the mucin1 protein by quenching dual emissions with ferrocene . Cui’s group constructed the biosensor of target-regulated conductivity to enhance the dual signal of nGO@TiO 2 NLPs, achieving the ratiometric detection of cardiac troponin I .…”