Dual-protein visual detection using ratiometric fluorescent probe based on Rox-DNA functionalized CdZnTeS QDs

Structures and Applications of NIR‐II AIEgens Containing Benzobisthiadiazole Derivatives

“…Inorganic quantum dots are widely used in the fields of biosensors and bioimaging due to their wide excitation range and narrow emission spectrum, better light stability and simple synthesis. [56][57][58] At present, the synthesize of AIEgens quantum dots (QDs) (particle size less than 10 nm) for biological application becomes a major challenge because the existing organic particles were basically larger than 25 nm. The ideal size of AIEgens QDs is less than 10 nm, which are easier to be captured and imaged by cells without surface modification of any membrane penetrating peptides or other targeted molecules.…”

“…Traditional fluorescent organic dyes used for imaging usually exhibit wide emission band and narrow excitation wavelength. Inorganic quantum dots are widely used in the fields of biosensors and bioimaging due to their wide excitation range and narrow emission spectrum, better light stability and simple synthesis [56–58] . At present, the synthesize of AIEgens quantum dots (QDs) (particle size less than 10 nm) for biological application becomes a major challenge because the existing organic particles were basically larger than 25 nm.…”

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

“…The different dispersions of CQDs before and aer the addition of Pro revealed that the CQDs assembled and integrated with Pro for the aggregation-caused quenching. [29][30][31][32][33] The interacting patterns between CQDs and Pro in CQDs/Pro were also investigated. The zeta potential and particle size distribution were characterized, as shown in Fig.…”

“…Thus, combined with the results of the zeta potential and varied size, it can be concluded that electrostatic interaction is the main factor that induces negative CQDs to aggregate and quench with the addition of positive Pro in the formed CQDs/Pro. 31 The testing principles of TRY using CQDs/Pro were further investigated. The simple presence of Try in CQDs could not modulate the negatively charged CQDs, indicating the absence of any interaction between CQD and Try (Fig.…”

Ratiometric Detection of Al Based on the Mixing of D‐penicillamine‐Functionalized Copper Nanoclusters with Pyridoxal 5’‐phosphate

“…[19] Mao et al developed a simple and sensitive method for the detection of protamine and trypsin by a ratiometric fluorescent probe based on Rox-DNA functionalized CdZnTeS quantum dots (QDs). [20] Among these fluorescent materials, the ultra-small fluorescent metal (Cu, Ag and Au) nanoclusters (MNCs) have been widely used as light-emitting units owing to their advantageous optical properties (like high luminescence intensity, excellent stability, low toxicity, large stokes displacement and good biocompatibility [21,24] ). In particular, copper nanoclusters (CuNCs) began to attract increasing interest, due to not only their high yield under mild synthetic conditions but also the excellent water solubility and biocompatibility of most CuNCs.…”