Dual renin-angiotensin blockage and total embryo cryopreservation is not a risk-free strategy in patients at high risk for ovarian hyperstimulation syndrome

Intravenous calcium infusion as a novel preventive therapy of ovarian hyperstimulation syndrome for patients with polycystic ovarian syndrome

“…This novel strategy for use in patients at high risk for OHSS did not completely eliminate the development of the syndrome (24). There are also concerns about the safety of the treatment as angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists have a possible teratogenic effect in humans (25).…”

Failure of fertility therapy and subsequent adverse cardiovascular events

“…40,41 Additional potential options to protect against thromboembolism might include the control of risk factors or prophylactic antiplatelet therapy. 42 In contrast, an observed decreased risk of coronary events following fertility therapy failure appears inconsistent with the hypothesis that endothelial dysfunction may already be present in women at risk of miscarriage and may become accentuated by fertility therapy failure.…”

Ovarian hyperstimulation syndrome: pathophysiology and prevention

“…Renin-angiotensin system blockade Two series of cases [33,34] have reported the use of a dual blockage combining the use of an angiotensin receptor blocker and an angiotensin-converting enzyme inhibitor. Considering both studies, fourteen high-risk women (estradiol >8,000 pg/ml) were studied, and two cases of moderate/severe OHSS occurred (14.4%).…”