Dual-Signal Integrated Aptasensor for Microcystin-LR Detection via In Situ Generation of Silver Nanoclusters Induced by Circular DNA Strand Displacement Reactions

A Co-Reactive Immunosensor Based on Ti3C2Tx MXene@TiO2–MoS2 Hybrids Promoting luminol@Au@Ni–Co NCs Electrochemiluminescence for CYFRA 21–1 Detection

“…The experimental conditions were optimized to further enhance the signal from the immunosensor. − In this experiment, the concentration of the substrate material Ti 3 C 2 T x MXene@TiO 2 –MoS 2 , pH of PBS, the concentration of the co-reactant (H 2 O 2 ), and the Ab 2 incubation time were optimized. First of all, the optimization of Ti 3 C 2 T x MXene@TiO 2 –MoS 2 hybrid concentration was particularly important as a sensing substrate.…”

Novel Efficient Selenium-Based D−π–A NIR Polymer Dots Anodic Electrochemiluminescence Emitter and Its Application in Simultaneous Detection of Two Pneumonia Pathogens with CdS Quantum Dots

“…The Se-Pdots were prepared in an aqueous solution using nanoprecipitation. 12 Briefly, stock solutions of the copolymer and poly(styrene-co-maleic anhydride) PSMA were prepared in THF at a concentration of 1 mg mL −1 to obtain a mixture containing 100 μg mL −1 copolymer and 20 μg mL −1 PSMA. After subjecting the mixture to ultrasonic degassing for 20 min, a sample of 2 mL was immediately added to 10 mL of ultrapure water in an active bath sonicator (120 W, 37 kHz) and sonicated for a duration of 4 min.…”

“…Owing to their excellent biocompatibility, nontoxic nature, facile functionalization, high photostability, and adjustable luminescence properties, Pdots have rapidly developed and widely used in biological and chemical analyses . Recent investigations have reported on the ECL of Pdots based on a donor–acceptor (D–A) strategy; however, their ECL emissions are primarily confined to the visible region. − Inspired by the above strategy, a ternary component (donor–bridge–acceptor) strategy was proposed to prepare NIR ECL Pdots, resulting in red-shifted absorption and emission wavelengths. Incorporation of π-bridge segments into the polymer backbone can also enhance the steric hindrance effect, thereby alleviating the quenching phenomenon induced by nanoparticle aggregation and facilitating efficient energy transfer from the donor moiety to the acceptor moiety. , Moreover, the element selenium (Se) is a crucial constituent in the synthesis of NIR ECL QDs, but there are no reports on Se-containing organic polymer materials exhibiting NIR ECL properties so far.…”

An electrochemiluminescence microsensor based on DNA-silver nanoclusters amplification for detecting cellular adenosine triphosphate

“…Wang's group synthesized fluorescence enhanced oligonucleotide-templated metal nanoclusters such as DNA-AuNCs and DNA-CuNCs for sensitive detection of l -histidine, trypsin, and tetracycline. 13–16 DNA-AgNCs can be easily synthesized through reduction of special DNA stabilized silver ions, 17 exhibiting tunable fluorescence emission and high photostability compared with usual silver nanoparticles. 18–21 The high affinity of cytosine in single-stranded DNA (ssDNA) to Ag + makes it convenient for the in situ generation of AgNCs.…”