2024
DOI: 10.1186/s13567-024-01338-2
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Duck STING mediates antiviral autophagy directing the interferon signaling pathway to inhibit duck plague virus infection

Bin Tian,
Yanming Tian,
Xuetong Wang
et al.

Abstract: Migratory birds are important vectors for virus transmission, how migratory birds recognize viruses and viruses are sustained in birds is still enigmatic. As an animal model for waterfowl among migratory birds, studying and dissecting the antiviral immunity and viral evasion in duck cells may pave a path to deciphering these puzzles. Here, we studied the mechanism of antiviral autophagy mediated by duck STING in DEF cells. The results collaborated that duck STING could significantly enhance LC3B-II/I turnover,… Show more

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