In this letter, we analyze the topological response of a fermionic model defined on the Lieb lattice in presence of an electromagnetic field. The tight-binding model is built in terms of three species of spinless fermions and supports a topological Varma phase due to the spontaneous breaking of timereversal symmetry. In the low-energy regime, the emergent effective Hamiltonian coincides with the so-called Duffin-Kemmer-Petiau (DKP) Hamiltonian, which describes relativistic pseudospin-0 quasiparticles. By considering a minimal coupling between the DKP quasiparticles and an external Abelian gauge field, we first find the Landau-level spectrum by fixing the Landau gauge; then we compute the emergent Chern-Simons theory for a weak-electromagnetic-field regime. The corresponding Hall conductivity reveals an atypical quantum Hall effect, which can be simulated in an artificial Lieb lattice.