Duodenal mature teratoma causing partial intestinal obstruction: A first case report in an adult

Duodenal teratoma: Rare case of extragonadal germ cell tumors and review of literature

“…GCTs are tumors that derive from neoplastic germ cells, and they have their extragonadal counterpart; they are morphologically similar [1] . GCTs usually originate in the gonads, whereas EGCTs are found in different places, the majority of which are found at the midline level of the body; as if the germ cell precursors had mistakenly stopped there as they migrated to their final position during embryogenesis [7] , via dorsal mesentery of the hindgut from endoderm of yolk sac to gonads; [5] several extragonadic locations are reported from which we mention head and neck, brain, mediastinum, abdominal wall, retroperitoneum and sacrococcygeal region [2] .…”

“…Teratomas are therefore neoplasms formed by a mixture of dermal tissue of two or three origins [11] , deriving from the three germ layers: the ectoderm, the endoderm and the mesoderm, and with different level of maturity and differentiation [2] . Only 1% will undergo a malignant transformation mostly in squamous cell carcinoma [2] , they risk having an aggressive and metastatic pattern [1] .…”

“…Teratoma is one of the morphological types of EGGCTs; [1] it is made up of tissues originating from multiple germ layers, and it is divided into categories according to its degree of maturity [2] . Its embryonic origin is debatable and several concepts have been developed from 1908 to nowadays, but they can be assumed to be congenital pathologies [3] .…”

“…Extragonadic teratomas are rare, and those which are rising from duodenum are among the rarest [2] . Herein, we present the fifth case of primary duodenal teratoma and the second case occurring in an adult, this is a case of 26-years-old male, who has been diagnosed with mature duodenal teratoma as a cause of abdominal pain and anemia, and treated by an oncologic resection.…”

Immature Teratoma of the Ileum—a Case Report and Literature Review

“…The mesentery and bowel are extremely rare sites of teratoma. Very few cases of mesenteric teratoma [3] and two cases of bowel teratoma have been reported [4]. Both the cases of bowel teratomas reported earlier were mature type.…”