Duplicate growth hormone genes in sheep and goat

Wallis, Michael; Lioupis, A; Wallis, O. Caryl

doi:10.1677/jme.0.0210001

Cited by 55 publications

(44 citation statements)

References 28 publications

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“…Duplication of the GH gene was first discovered in primates but further investigation indicated that this event had also occurred in rats, pigs, goats, sheep and cattle (Charrier and Martal, 1988;Wallis et al, 1998). In cattle the two major allelic variants of GH, denoted A (leucine at position 127) and B (valine at position 127), have been identified by Lucy et al, 1993).…”

Section: Basic Physiology Nutritional Factors Influencing Thyroid Fumentioning

confidence: 99%

Clinical endocrinology of thyroid gland function in ruminants

Huszenicza¹,

Kulcsár²,

Rudas³

2002

Vet. Med.

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After briefly introducing the basec steps in production and metabolism of thyroid hormones, the author gives an overview of nutritional, metabolic and disease related factors and endocrine interactions influencing thyroid gland function in ruminants, particularly in the postpartum dairy cow. Involvement of thyroid hormonal regulation of seasonal patterns of reproduction as well as ovarian endocrine function are discussed.Keywords: thyroxin; triiodothyronine; ovary; metabolism; ruminants Abbreviations: 5'D = 5'-deiodinase (syn.: outer-ring deiodinase); 5D = 5-deiodinase (syn.: inner-ring deiodinase); BHB = βOH-butyrate; E 2 = 17β-estradiol; FSH = follicle stimulating hormone; GH = growth hormone; GnRH = gonadotropin releasing hormone; hCG = human chorionic gonadotropin; IGF-I = insulin-like growth factor-I (syn.: somatomedin C); IL = interleukin; LH = luteinizing hormone; mRNA = messenger ribonucleic acid; NEB = negative energy balance; NEFA = non-esterified fatty acids; P 4 = progesterone; PVN = paraventricular nucleus of the hypothalamus; rT 3 = 3,3',5'-triiodothyronine (syn.: reverse-triiodothyronine); T 3 = 3,3',5-triiodothyronine; T 4 = thyroxine; TNFα = tumor necrosis factor-α; TRH = thyrotropin-releasing hormone; TSH = thyroid-stimulating hormone (syn.: thyrotropin)

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Section: Basic Physiology Nutritional Factors Influencing Thyroid Fumentioning

confidence: 99%

Clinical endocrinology of thyroid gland function in ruminants

Huszenicza¹,

Kulcsár²,

Rudas³

2002

Vet. Med.

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“…Association of several polymorphic sites (SNPs) in different candidate genes with economic traits has been much investigated in different animal species. Work based on characterization of candidate genes and their association with animal performance in camels is meagre compared with cattle (Lucy et al, 1991;Schlee et al, 1994;Ge et al, 2003), sheep (Wallis et al, 1998;Bastos et al, 2001) or goats (Wallis et al, 1998;Neelam Gupta et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Phenotypic and molecular characterization of six Sudanese camel breeds

Ishag¹,

Reißmann²,

Peters³

et al. 2011

SA J. An. Sci.

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The objective of this study was to sequence the growth hormone (GH) gene in Sudanese camel breeds (Kenani, Lahwee, Rashaidi, Anafi, Bishari and Kabbashi) searching for single nucleotide polymorphisms (SNPs) and contribute to the phenotypic characterization of the multitude of camel ecotypes in Sudan. This will also afford the chance of investigating the possibility of the presence of correlations between body measurements and SNPs of GH gene. A length of 1732 bp, spanning the region between -44 bp upstream of the first exon and +37 bp downstream of the last exon was sequenced in two animals from each breed. The sequence comparison of Sudanese camel GH sequences with the GenBank sequence identified one single nucleotide polymorphism (SNP). The SNP was detected in the non coding region (intron 1) in position AJ575419:g.419C>T. A PCR-RFLP method was used to genotype 181 animals representing the six tested Sudanese breeds for detected SNP. The Bishari and Anafi breeds that are classified as riding camels had slightly higher T allele frequencies (0.57 and 0.48, respectively) than those of the other four breeds which are classified as pack camels. The effect of genotype with regard to the SNP g.419C>T on those traits was not significant. ________________________________________________________________________________

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“…Wheatley et al (1966) found that growth hormone suppressed wool growth and that there was accelerated wool growth after withdrawal of growth hormone. Polymorphism at the genes encoding growth hormone have been reported (Valinsky et al, 1990;Wallis et al, 1998;Sami et al, 1999), and different alleles of growth hormone may affect wool growth in different ways.…”

Section: Resultsmentioning

confidence: 99%

Identification of Polymorphism in the Keratin Genes (KAP3.2, KAP6.1, KAP7, KAP8) and Microsatellite BfMS in Merino Sheep Using Polymerase Chain Reaction-Single Strand Conformational Polymorphism (PCR-SSCP) Analysi

Itenge¹

2012

Electrophoresis

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Duplicate growth hormone genes in sheep and goat

Cited by 55 publications

References 28 publications

Clinical endocrinology of thyroid gland function in ruminants

Clinical endocrinology of thyroid gland function in ruminants

Phenotypic and molecular characterization of six Sudanese camel breeds

Identification of Polymorphism in the Keratin Genes (KAP3.2, KAP6.1, KAP7, KAP8) and Microsatellite BfMS in Merino Sheep Using Polymerase Chain Reaction-Single Strand Conformational Polymorphism (PCR-SSCP) Analysi

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