“…The O-ring used in the SAVY-4000 has been identified as one of the lifetime-limiting components of the design, and it is a part that is vulnerable to wear through repeated use. Preliminary studies detailed 4,5 the basic properties, composition and durability of the SAVY-4000 O-rings. However, the fluoropolymer-based O-ring may deteriorate over time due to compression, elevated temperatures, and exposure to ionizing radiation.…”